Silverman J F, Levine J, Finley J L, Larkin E W, Norris H T
Department of Clinical Pathology and Diagnostic Medicine, East Carolina University School of Medicine, Greenville, NC 27834.
Diagn Cytopathol. 1990;6(3):193-6. doi: 10.1002/dc.2840060309.
We report the cytologic findings of small intestinal brushing material showing cryptosporidiosis in two patients with acquired immunodeficiency syndrome (AIDS). Cryptosporidia measuring approximately 2-4 mu were aligned along the surface of the glandular cells, although many freely dispersed organisms were also present. The differential diagnoses of other structures that could be confused with cryptosporidia are also presented in this article. Small-intestinal brushing cytology may complement endoscopic biopsy in the workup of diarrheal diseases in AIDS, especially in patients with thrombocytopenia, since the bleeding disorder may be a contraindication for endoscopic biopsy.
我们报告了两例获得性免疫缺陷综合征（AIDS）患者小肠刷检材料显示隐孢子虫病的细胞学发现。隐孢子虫大小约为2-4微米，沿腺细胞表面排列，不过也有许多自由分散的病原体。本文还介绍了可能与隐孢子虫混淆的其他结构的鉴别诊断。小肠刷检细胞学检查可辅助艾滋病腹泻疾病的检查，特别是对于血小板减少的患者，因为出血性疾病可能是内镜活检的禁忌证。
