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[邦内科尔——一种新型抗心律失常制剂]

[Bonnecor--a new anti-arrhythmia preparation].

作者信息

Berdiaev S Iu, Lyskovtsev V V, Senova Z P, Darinskiĭ N V, Grigor'eva E K, Tolmacheva E A, Turilova A I, Gritsenko A N, Kaverina N V

出版信息

Farmakol Toksikol. 1990 May-Jun;53(3):33-6.

PMID:2387376
Abstract

The antiarrhythmic properties of a new drug bonnecor being a derivative of dibenzazepine were studied on different models of arrhythmias. Bonnecor proved to be effective in the treatment of both atrial and ventricular arrhythmias of various genesis except rhythm disorders induced by ouabain intoxication. The drug was shown to exert a pronounced antifibrillatory effect and to increase the electrical stability of the intact and ischemic myocardium.

摘要

对一种新型药物bonnecor(二苯氮䓬衍生物)的抗心律失常特性在不同心律失常模型上进行了研究。结果证明,bonnecor除对哇巴因中毒引起的节律紊乱无效外,对各种起源的房性和室性心律失常均有治疗效果。该药物显示出显著的抗纤颤作用,并能提高完整和缺血心肌的电稳定性。

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