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In vitro characterization of gastrointestinal behavior of Butyricicoccus pullicaecorum, a novel butyrate producing isolate with probiotic potential to counterbalance dysbiosis in inflammatory bowel disease.

作者信息

Geirnaert A, Steyaert A, Van den Abbeele P, Eeckhaut V, Van Immerseel F, Boon N, Van de Wiele T

机构信息

Laboratory of Microbial Ecology and Technology (LabMET), Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Gent, Belgium.

出版信息

Commun Agric Appl Biol Sci. 2013;78(1):157-63.

PMID:23875313
Abstract
摘要

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1
In vitro characterization of gastrointestinal behavior of Butyricicoccus pullicaecorum, a novel butyrate producing isolate with probiotic potential to counterbalance dysbiosis in inflammatory bowel disease.pullicaecorum丁酸球菌是一种新型的产丁酸菌株，具有益生菌潜力，可对抗炎症性肠病中的生态失调，对其胃肠道行为进行体外表征。
Commun Agric Appl Biol Sci. 2013;78(1):157-63.
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In vitro evaluation of the upper gastrointestinal passage of a novel butyrate producing isolate to counterbalance dysbiosis in inflammatory bowel disease.
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In vitro evaluation of the upper gastrointestinal passage of a novel butyrate producing isolate to counterbalance dysbiosis in inflammatory bowel disease.一种新型产丁酸分离株在上消化道通过情况的体外评估，以平衡炎症性肠病中的生态失调。
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Interindividual differences in response to treatment with butyrate-producing Butyricicoccus pullicaecorum 25-3T studied in an in vitro gut model.在体外肠道模型中研究了产丁酸的普氏丁酸球菌25-3T治疗反应的个体差异。
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Butyricicoccus pullicaecorum, a butyrate producer with probiotic potential, is intrinsically tolerant to stomach and small intestine conditions.普氏丁酸球菌是一种具有产生丁酸能力且有潜在益生菌特性的细菌，其本身对胃和小肠环境具有耐受性。
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Safety assessment of the butyrate-producing Butyricicoccus pullicaecorum strain 25-3(T), a potential probiotic for patients with inflammatory bowel disease, based on oral toxicity tests and whole genome sequencing.基于口服毒性试验和全基因组测序对产丁酸的普氏丁酸球菌菌株25-3(T)进行安全性评估，该菌株是炎症性肠病患者的一种潜在益生菌。
Food Chem Toxicol. 2014 Oct;72:129-37. doi: 10.1016/j.fct.2014.06.024. Epub 2014 Jul 4.
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Butyricicoccus pullicaecorum gen. nov., sp. nov., an anaerobic, butyrate-producing bacterium isolated from the caecal content of a broiler chicken.盲肠丁酸球菌属，新属，新种，一种从肉鸡盲肠内容物中分离出的厌氧产丁酸细菌。
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Butyricicoccus pullicaecorum in inflammatory bowel disease.产丁酸梭菌与炎症性肠病。
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Butyrate Producers as Potential Next-Generation Probiotics: Safety Assessment of the Administration of to Healthy Volunteers.丁酸盐产生菌作为潜在的下一代益生菌：对健康志愿者给药的安全性评估
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Progress towards butyrate-producing pharmabiotics: Butyricicoccus pullicaecorum capsule and efficacy in TNBS models in comparison with therapeutics.产丁酸药物益生菌的研究进展：与治疗药物相比，普氏粪丁酸球菌胶囊及其在三硝基苯磺酸（TNBS）模型中的疗效
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