Vasiljevic J D, Abdulla A K
Institute of Pathology, Medical School, Belgrade, Yugoslavia.
Gynecol Oncol. 1990 Aug;38(2):289-92. doi: 10.1016/0090-8258(90)90058-s.
Although gestational choriocarcinoma is a rapidly invasive malignancy, metastatic invasion of this tumor to the heart is rare. We report an unusual case of coronary embolism, which was caused by malignant trophoblasts from choriocarcinoma in a 26-year-old woman. The woman presented with classic symptoms of ischemic heart disease after having successfully undergone chemotherapeutic treatment for choriocarcinoma several months earlier. Thus, she was thought to have coronary heart disease or to have developed cardiotoxicity from antineoplastic drugs. This is the first report of this type of metastatic localization and tumor involvement in the heart and underscores the need for suspecting isolated metastases in uncommon sites in patients with choriocarcinoma.
尽管妊娠性绒毛膜癌是一种侵袭性迅速的恶性肿瘤，但该肿瘤转移至心脏的情况罕见。我们报告了一例不寻常的冠状动脉栓塞病例，其由一名26岁女性绒毛膜癌的恶性滋养层细胞引起。该女性在数月前成功接受绒毛膜癌化疗后，出现了缺血性心脏病的典型症状。因此，她被认为患有冠心病或因抗肿瘤药物产生了心脏毒性。这是此类转移定位及肿瘤累及心脏的首例报告，并强调了对于绒毛膜癌患者，需怀疑在不常见部位出现孤立转移的必要性。
