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镁对子宫自发性收缩的抑制作用。镁剂保胎治疗

[Inhibition of spontaneous uterine contractions by magnesium. Magnesium tocolysis].

作者信息

Lechner W, Mayr P, Marth C

机构信息

Universitäts-Klinik für Frauenheilkunde, Innsbruck, Osterreich.

出版信息

Gynakol Rundsch. 1990;30(2):69-73.

PMID:2387545
Abstract

A state of magnesium deficiency has been established in the population of highly industrialized countries in the last few years. This results among other disturbancies, in increasing prematurity. Therefore the tocolytic activity of magnesium was investigated in 29 uterine strips, which were obtained during cesarean section. A highly significant (p less than 0.001) reduction of the uterine activity from 100 to 0 (0-21), 0 (0-0) and 0 (0-0) (median, 20th and 80th percentile) 10, 20 and 60 min after the application of magnesium was observed.

摘要

在过去几年里,高度工业化国家的人群中已出现镁缺乏状态。这除了引发其他紊乱外,还导致早产率上升。因此,对剖宫产术中获取的29条子宫肌条进行了镁的宫缩抑制活性研究。观察到应用镁后10分钟、20分钟和60分钟时子宫活性从100显著降低至0(中位数,第20百分位数和第80百分位数分别为0(0 - 21)、0(0 - 0)和0(0 - 0))(p < 0.001)。

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