Department of Poultry Science, University of Arkansas, Fayetteville, Arkansas, USA.
Adv Parasitol. 2013;83:93-171. doi: 10.1016/B978-0-12-407705-8.00002-1.
Coccidiosis is a widespread and economically significant disease of livestock caused by protozoan parasites of the genus Eimeria. This disease is worldwide in occurrence and costs the animal agricultural industry many millions of dollars to control. In recent years, the modern tools of molecular biology, biochemistry, cell biology and immunology have been used to expand greatly our knowledge of these parasites and the disease they cause. Such studies are essential if we are to develop new means for the control of coccidiosis. In this chapter, selective aspects of the biology of these organisms, with emphasis on recent research in poultry, are reviewed. Topics considered include taxonomy, systematics, genetics, genomics, transcriptomics, proteomics, transfection, oocyst biogenesis, host cell invasion, immunobiology, diagnostics and control.
球虫病是一种广泛存在且具有重要经济意义的家畜疾病,由艾美耳属的原生动物寄生虫引起。这种疾病在世界范围内发生,给动物农业产业造成了数百万美元的控制成本。近年来,分子生物学、生物化学、细胞生物学和免疫学的现代工具被用于极大地扩展我们对这些寄生虫及其引起的疾病的认识。如果我们要开发控制球虫病的新方法,这些研究是必不可少的。在本章中,选择性地回顾了这些生物体的生物学,重点是家禽的最新研究。讨论的主题包括分类学、系统学、遗传学、基因组学、转录组学、蛋白质组学、转染、卵囊发生、宿主细胞入侵、免疫生物学、诊断和控制。