From the *University of Alabama at Birmingham, Birmingham; and †Birmingham VA Medical Center (BVAMC), Birmingham, AL.
Clin Nucl Med. 2014 Jun;39(6):551-3. doi: 10.1097/RLU.0b013e31829f913d.
Papillary thyroid carcinoma (PTC) is the most common malignancy of thyroid gland. Though it metastasizes primarily through lymphatics, hematogenous spread is not infrequent. We report the case of a 62-year-old male patient with intraventricular choroid plexus metastasis from PTC, incidentally detected on post-high-dose radioiodine therapy whole-body I scan, which is an extremely rare presentation. Only 3 cases of choroid plexus metastasis from thyroid carcinoma have been reported. Further multimodality radiological investigations confirmed diagnosis and helped in assessing treatment response. The patient received gamma-knife stereotactic radiosurgery, and follow-up radiological imaging suggested improvement of intracranial metastasis.
甲状腺乳头状癌(PTC)是甲状腺最常见的恶性肿瘤。虽然它主要通过淋巴途径转移,但血行播散并不少见。我们报告了一例 62 岁男性患者,因 PTC 发生脑室脉络丛转移,在高剂量放射性碘治疗后全身 I 扫描时偶然发现,这是一种极其罕见的表现。仅有 3 例甲状腺癌脉络丛转移的病例报道。进一步的多模态影像学检查证实了诊断,并有助于评估治疗反应。患者接受了伽玛刀立体定向放射外科治疗,随访影像学检查提示颅内转移灶改善。