Healy Andrew T, Otvos Balint, Schroeder Jason, Hamrahian Amir H, Angelov Lilyana, Kamian Kambiz
Department of Neurosurgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
Case Western Reserve University, Lerner College of Medicine, Cleveland, OH, USA.
J Clin Neurosci. 2014 Aug;21(8):1448-50. doi: 10.1016/j.jocn.2013.12.012. Epub 2014 Jan 24.
Choroid plexus masses represent approximately 0.3-0.8% of intracranial tumors. Herein we present, to our knowledge, the first reported patient with an isolated Hurthle cell papillary thyroid carcinoma metastasis to the choroid plexus of the lateral ventricle. Unresponsive to iodine ablation and refusing surgery, the patient underwent Gamma Knife radiosurgery (Elekta AB, Stockholm, Sweden), receiving 15Gy to the 50% isodose line. The lesion regressed until 5years later at which time it was unresponsive to 18Gy and required surgical resection. Although extraneural metastatic cancers are recognized as potential sources for the single choroid plexus mass, we must consider even the unusual culprit in patients with a history of cancer.
脉络丛肿瘤约占颅内肿瘤的0.3 - 0.8%。据我们所知，本文报告了首例孤立性嗜酸性细胞乳头状甲状腺癌转移至侧脑室脉络丛的患者。该患者对碘消融治疗无反应且拒绝手术，遂接受了伽玛刀放射外科治疗（瑞典斯德哥尔摩的医科达公司），50%等剂量线处给予15Gy照射。病灶缩小，直至5年后对18Gy照射无反应，需要进行手术切除。虽然神经外转移癌被认为是单一脉络丛肿块的潜在来源，但对于有癌症病史的患者，我们甚至必须考虑到不常见的病因。
