Sugita-Kitajima Akemi, Koizuka Izumi
Department of Otolaryngology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan.
Department of Otolaryngology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan.
Auris Nasus Larynx. 2014 Feb;41(1):22-6. doi: 10.1016/j.anl.2013.04.014. Epub 2013 Jul 20.
The vestibulo-ocular reflex (VOR) was studied to determine the utility of off-vertical axis rotation (OVAR) in evaluating vestibular function in patients with canal paresis (CP). Our goal was to determine whether there is any correlation between caloric responses and sinusoidal rotatory responses.
Subjects were rotated in a sinusoidal pattern with eyes open in complete darkness. Frequencies of 0.4 and 0.8Hz with a maximum angular velocity of 60°/s at either earth-vertical axis rotation (EVAR) or OVAR were used.
Twenty-three control subjects and 21 patients with CP were investigated. Results showed that (1) the VOR gain difference between EVAR and OVAR in the CP patients was not significant at 0.4Hz and at 0.8Hz; (2) the gain during 0.4Hz EVAR was less in the bilateral CP patients compared to controls; and (3) the VOR gain of the affected side at 0.8Hz was significantly less during OVAR than during EVAR.
We concluded that the absence or reduction of caloric responses does not indicate the absence of vestibular function. In addition, separation analysis of the VOR gain of affected and intact sides is useful for evaluating laterality of otolith function in patients with CP.
研究前庭眼反射（VOR），以确定非垂直轴旋转（OVAR）在评估半规管麻痹（CP）患者前庭功能中的效用。我们的目标是确定冷热试验反应与正弦旋转反应之间是否存在任何相关性。
让受试者在完全黑暗中睁眼以正弦模式旋转。采用0.4和0.8Hz的频率，在地球垂直轴旋转（EVAR）或OVAR时最大角速度为60°/秒。
对23名对照受试者和21名CP患者进行了研究。结果表明：（1）CP患者在0.4Hz和0.8Hz时，EVAR和OVAR之间的VOR增益差异不显著；（2）与对照组相比，双侧CP患者在0.4Hz EVAR期间的增益较低；（3）在0.8Hz时，患侧在OVAR期间的VOR增益明显低于EVAR期间。
我们得出结论，冷热试验反应的缺失或降低并不表明前庭功能的缺失。此外，对患侧和健侧VOR增益进行分离分析，有助于评估CP患者耳石功能的偏向性。
