Department of Otorhinolaryngology, University Medical Center Utrecht, Heidelberglaan 100, G05. 129, 3584 CX, Utrecht, The Netherlands,
Eur Arch Otorhinolaryngol. 2014 Jun;271(6):1477-83. doi: 10.1007/s00405-013-2624-8. Epub 2013 Jul 24.
High-speed thermal imaging enables visualization of heating of the vestibule during laser-assisted stapedotomy, comparing KTP, CO2, and Thulium laser light. Perforation of the stapes footplate with laser bears the risk of heating of the inner ear fluids. The amount of heating depends on absorption of the laser light and subsequent tissue ablation. The ablation of the footplate is driven by strong water absorption for the CO2 and Thulium laser. For the KTP laser wavelength, ablation is driven by carbonization of the footplate and it might penetrate deep into the inner ear without absorption in water. The thermal effects were visualized in an inner ear model, using two new techniques: (1) high-speed Schlieren imaging shows relative dynamic changes of temperatures up to 2 ms resolution in the perilymph. (2) Thermo imaging provides absolute temperature measurements around the footplate up to 40 ms resolution. The high-speed Schlieren imaging showed minimal heating using the KTP laser. Both CO2 and Thulium laser showed heating below the footplate. Thulium laser wavelength generated heating up to 0.6 mm depth. This was confirmed with thermal imaging, showing a rise of temperature of 4.7 (±3.5) °C for KTP and 9.4 (±6.9) for Thulium in the area of 2 mm below the footplate. For stapedotomy, the Thulium and CO2 laser show more extended thermal effects compared to KTP. High-speed Schlieren imaging and thermal imaging are complimentary techniques to study lasers thermal effects in tissue.
高速热成像可用于可视化激光辅助镫骨切开术中前庭加热,比较 KTP、CO2 和铥激光。用激光穿透镫骨底板会有内耳液加热的风险。加热量取决于激光的吸收和随后的组织消融。CO2 和铥激光的强烈水吸收驱动底板的消融。对于 KTP 激光波长,底板的消融是由碳化驱动的,它可能在没有水吸收的情况下深入内耳。使用两种新技术在内耳模型中可视化了热效应:(1)高速纹影成像以 2ms 的分辨率显示可达内淋巴的相对动态温度变化。(2)热成像提供可达 40ms 分辨率的底板周围的绝对温度测量。高速纹影成像显示 KTP 激光加热最小。CO2 和铥激光均显示底板下方加热。铥激光波长产生的加热深度可达 0.6mm。热成像证实了这一点,显示在距底板下方 2mm 的区域内,KTP 的温度升高了 4.7(±3.5)℃,铥的温度升高了 9.4(±6.9)℃。对于镫骨切开术,铥和 CO2 激光与 KTP 相比显示出更广泛的热效应。高速纹影成像和热成像技术是研究激光在组织中热效应的互补技术。