Koenraads Simone P C, de Boorder Tjeerd, Grolman Wilko, Kamalski Digna M A
Department of Otorhinolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands.
Department of Medical Technology and Clinical Physics, University Medical Center Utrecht, Utrecht, The Netherlands.
Lasers Surg Med. 2017 Aug;49(6):619-624. doi: 10.1002/lsm.22649. Epub 2017 Apr 11.
Multiple laser systems have been investigated for their use in stapes surgery in patients with otosclerosis. The diode 1,470 nm laser used in this study is an attractive laser system because it is easily transported and relatively inexpensive in use. This wavelength has relative high absorption in water. This study aimed to investigate the mechanical, thermal, and acoustic effects of the diode 1,470 nm laser on a stapes in an inner ear model.
Experiments were performed in an inner ear model including fresh frozen human stapes. High-speed imaging with frame rates up to 2,000 frames per second (f/s) was used to visualize the effects in the vestibule during fenestration of the footplate. A special high-speed color Schlieren technique was used to study thermal effects. The sound produced by perforation was recorded by a hydrophone. Single pulse settings of the diode 1,470 nm laser were 100 ms, 3 W.
Diode 1,470 nm laser fenestration showed mechanical effects with small vapor bubbles and pressure waves pushed into the vestibule. Thermal imaging visualized an increase temperature underneath the stapes footplate. Acoustic effects were limited, but larger sounds levels were reached when vaporization bubbles arise and explode in the vestibule.
The diode 1,470 nm laser highly absorbs in perilymph and is capable of forming a clear fenestration in the stapes. An overlapping laser pulse will increase the risk of vapor bubbles, pressure waves, and heating the vestibule. As long as we do not know the possible damage of these effects to the inner ear function, it seems advisable to use the laser with less potential harm. Lasers Surg. Med. 49:619-624, 2017. © 2017 Wiley Periodicals, Inc.
多种激光系统已被研究用于耳硬化症患者的镫骨手术。本研究中使用的1470纳米二极管激光是一种有吸引力的激光系统,因为它易于运输且使用成本相对较低。该波长在水中具有较高的吸收率。本研究旨在探讨1470纳米二极管激光在内耳模型中对镫骨的机械、热和声效应。
实验在内耳模型中进行,该模型包括新鲜冷冻的人镫骨。使用高达每秒2000帧(f/s)的高速成像技术来观察镫骨足板开窗时前庭内的效应。采用一种特殊的高速彩色纹影技术来研究热效应。穿孔产生的声音由水听器记录。1470纳米二极管激光的单脉冲设置为100毫秒、3瓦。
1470纳米二极管激光开窗显示出机械效应,有小气泡和压力波被推入前庭。热成像显示镫骨足板下方温度升高。声效应有限,但当汽化气泡在前庭中产生并爆炸时会达到更高的声级。
1470纳米二极管激光在外淋巴中具有高吸收率,能够在镫骨上形成清晰的开窗。重叠激光脉冲会增加产生气泡、压力波以及加热前庭的风险。在我们尚不清楚这些效应对内耳功能可能造成的损害之前,使用潜在危害较小的激光似乎是明智的。《激光外科与医学》49:619 - 624, 2017。© 2017威利期刊公司