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通过母体免疫预防新生儿感染。

Preventing newborn infection with maternal immunization.

机构信息

Center for Global Health, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.

出版信息

Sci Transl Med. 2013 Jul 24;5(195):195ps11. doi: 10.1126/scitranslmed.3005451.

Abstract

Group B streptococcal disease is a common cause of bacterial sepsis in newborns and is often fatal. To protect these babies, a vaccination program must target pregnant women for immunization so that the resulting antibodies can be passively delivered from the mother to the fetus. Scientists met in Siena, Italy, to discuss potential approaches to maternal immunization for the prevention of perinatal group B streptococcal disease.

摘要

B 群链球菌疾病是新生儿细菌性败血症的常见病因,且通常具有致命性。为了保护这些婴儿,疫苗接种计划必须针对孕妇进行免疫接种,以便由此产生的抗体可以从母亲被动传递给胎儿。科学家们在意大利锡耶纳开会,讨论预防围产期 B 群链球菌病的母体免疫接种的潜在方法。

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