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2010 - 2012年25例蜱瘫痪犬肺部的组织病理学变化

Histopathological changes in the lungs from dogs with tick paralysis: 25 cases (2010-2012).

作者信息

Webster R A, Mackie J T, Haskins S C

机构信息

Animal Emergency Service, 104 Eastlake St, Carrara, Queensland, 4211, Australia.

出版信息

Aust Vet J. 2013 Aug;91(8):306-11. doi: 10.1111/avj.12085.

DOI:10.1111/avj.12085
PMID:23889095
Abstract

OBJECTIVE

To determine the prevalence and nature of histological lung lesions in dogs with tick paralysis.

METHODS

A prospective study of 25 client-owned dogs that died during treatment for tick paralysis or were euthanased because of either the severity of the disease process or financial constraints was conducted at a veterinary emergency hospital in Queensland, Australia. Lung specimens were collected postmortem for histopathological examination.

RESULTS

All 25 dogs had significant pulmonary changes: 9 exhibited congestion and alveolar oedema, with no obvious inflammatory cell infiltrate; 1 exhibited a mild increase in the number of alveolar macrophages in addition to congestion and alveolar oedema; the remaining 15 dogs had moderate or severe bronchopneumonia, with 2 showing evidence of aspiration pneumonia.

CONCLUSION

Dogs with clinically severe tick paralysis are likely to have pulmonary parenchymal disease. Bronchopneumonia may be present in a significant proportion of cases and may reflect aspiration.

摘要

目的

确定蜱瘫痪犬组织学肺部病变的患病率及性质。

方法

在澳大利亚昆士兰州的一家兽医急诊医院,对25只因蜱瘫痪接受治疗期间死亡或因病情严重程度或经济限制而实施安乐死的客户拥有的犬进行了一项前瞻性研究。死后采集肺标本进行组织病理学检查。

结果

所有25只犬均有明显的肺部变化:9只表现为充血和肺泡水肿,无明显炎性细胞浸润;1只除充血和肺泡水肿外,肺泡巨噬细胞数量轻度增加;其余15只犬患有中度或重度支气管肺炎,2只显示有吸入性肺炎的证据。

结论

临床上严重蜱瘫痪的犬可能患有肺实质疾病。相当一部分病例可能存在支气管肺炎,且可能反映有吸入情况。

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