Shinagawa LASIK Center, Chiyoda-ku, Tokyo, Japan.
J Cataract Refract Surg. 2013 Aug;39(8):1260-6. doi: 10.1016/j.jcrs.2013.05.025.
We report 2 cases of Cogan syndrome that developed after uneventful laser in situ keratomileusis. In the first case, an 8-month postoperative biomicroscopy revealed bilateral interface neovascularization, white intrastromal deposits, and anterior chamber cells and flare. In the second case, white cell infiltration and neovascularization were observed in the deep corneal stroma of the patient's right eye 18 months postoperatively. Based on these observations, which are consistent with typical interstitial keratitis, and the patients' history of Meniere-like disease, such as vertigo and mild hearing loss, Cogan syndrome was diagnosed in both patients. Topical steroids were prescribed. Intensive treatments with corneal irrigation and topical steroids showed effective outcomes in both cases.
我们报告了 2 例在无并发症的准分子激光原位角膜磨镶术后发生的 Cogan 综合征。在第一个病例中,术后 8 个月的生物显微镜检查显示双侧界面新生血管、白色基质内沉积物和前房细胞和闪光。在第二个病例中,患者右眼术后 18 个月观察到深层角膜基质中的白细胞浸润和新生血管形成。基于这些观察结果,与典型的间质性角膜炎一致,以及患者梅尼埃病样疾病的病史,如眩晕和轻度听力损失,在这两例患者中均诊断为 Cogan 综合征。给予局部皮质类固醇治疗。角膜冲洗和局部皮质类固醇的强化治疗在两种情况下均显示出有效结果。