London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.
J Arthroplasty. 2013 Sep;28(8 Suppl):83-6. doi: 10.1016/j.arth.2013.03.034. Epub 2013 Jul 24.
A total of 6275 consecutive TKA patients were divided into three groups based on their age: <55, 55-70 and >70 years. There was a statistically significant difference in the change in WOMAC score (32 vs 31 vs 26, P<0.001) and Knee Society Score (78.9 vs 76.0 vs 69.0, P<0.001) favoring the younger populations. However, the revision rate was higher in the younger patients with a Kaplan-Meier survivorship at 5 years of 95.5%, 97.2% and 98.1% and at 10 years of 92.2%, 95.9% and 97.6%. Infection was the most frequent cause for failure in all groups although aseptic loosening and instability accounted for the increased revision rate in the younger patients. Younger patients may experience slightly better clinical outcomes following TKA but lower survivorship, when compared to older patient populations.
共有 6275 例连续 TKA 患者根据年龄分为三组：<55 岁、55-70 岁和>70 岁。在 WOMAC 评分（32 分、31 分、26 分，P<0.001）和膝关节协会评分（78.9 分、76.0 分、69.0 分，P<0.001）的变化方面，年轻患者具有统计学显著差异，这表明年轻患者更具优势。然而，年轻患者的翻修率更高，5 年 Kaplan-Meier 生存率为 95.5%、97.2%和 98.1%，10 年生存率为 92.2%、95.9%和 97.6%。尽管无菌性松动和不稳定是年轻患者翻修率增加的原因，但感染是所有组中失败的最常见原因。与老年患者群体相比，年轻患者在接受 TKA 后可能会经历稍好的临床结果，但生存率较低。
