Division for Infection Control, Bernhard Gottlieb University Clinic of Dentistry, Vienna, Austria.
Am J Infect Control. 2013 Nov;41(11):1007-11. doi: 10.1016/j.ajic.2013.05.004. Epub 2013 Jul 25.
Hand hygiene is effective to prevent the transmission of microorganisms in health care settings, but compliance remains low, even when easy access to hand cleaning agents is provided.
Formulation of alcohol-based hand rub (ABHRs) may influence staff compliance to hand hygiene. The aim of this prospective longitudinal study (1 week) was to investigate possible differences of 4 different gel or liquid ABHR formulations, with or without virucidal claim among dental students.
Participants were randomly assigned to dental treatment cubicles, equipped with either a gel or a liquid based ABHRs, with our without a virucidal claim. Participants assessed the subjective acceptability and the tolerability of test formulations on their hands over a period of 1 week using the 14 item, 7-point Lickert scale World Health Organization questionnaire.
All tested ABHRs passed the subjective acceptability criteria of ≥50% above 4 for the items "color and fragrance" and for all other items of >75% above 4 and may be regarded as "good." Significant differences were observed between the 2 gels but not between the 2 liquid ABHRs. For subjective skin tolerability, no significant difference was observed between the liquid formulations after 1 consecutive week of application. However, the difference between the 2 gels was highly significant.
Virucidal ABHR formulations may be better accepted and tolerated over prolonged periods by dental students than anticipated. The user acceptability of ABHRs depend more on the specific product's formula than its general category.
手部卫生可有效预防医疗机构中微生物的传播，但即使提供了易于获得的手部清洁产品，其依从性仍然较低。
基于酒精的手部消毒剂（ABHR）的配方可能会影响工作人员对手部卫生的依从性。本前瞻性纵向研究（1 周）的目的是调查在牙科学生中，4 种不同凝胶或液体 ABHR 配方（具有或不具有杀病毒声称）之间是否存在差异。
参与者被随机分配到配备凝胶或液体 ABHR（具有或不具有杀病毒声称）的牙科治疗小隔间中。参与者在 1 周的时间内使用 14 项 7 分制 Likert 量表世界卫生组织问卷评估手部的主观可接受性和耐受性。
所有测试的 ABHR 均通过了主观可接受性标准，即“颜色和气味”的所有项目均超过 4 分，为 50%以上，而其他所有项目均超过 4 分，为 75%以上，可视为“良好”。在 2 种凝胶之间观察到显著差异，但在 2 种液体 ABHR 之间未观察到差异。在连续应用 1 周后，对于主观皮肤耐受性，液体制剂之间未观察到显著差异。但是，2 种凝胶之间的差异非常显著。
与预期相比，具有杀病毒声称的 ABHR 配方可能会被牙科学生更长时间地接受和耐受。ABHR 的用户可接受性更多地取决于特定产品的配方，而不是其一般类别。
