Ralevski Elizabeth, Gianoli Mayumi O, McCarthy Elissa, Petrakis Ismene
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, United States; Department of Veterans Affairs, VA Connecticut Healthcare System, West Haven, CT, United States; Mental Illness Research Education and Clinical Center, VA Connecticut Healthcare System, West Haven, CT, United States.
Addict Behav. 2014 Feb;39(2):386-91. doi: 10.1016/j.addbeh.2013.06.002. Epub 2013 Jun 13.
Quality of life is negatively impacted by diagnosis of mental illness. Those with mental illness report problems in physical, psychological, cognitive, social, and occupational functioning. This study was designed to examine changes in quality of life in veterans with dual diagnoses. All veterans participated in a treatment study designed to treat alcohol dependence with naltrexone, disulfiram, and the combination of naltrexone/disulfiram or placebo for 12 weeks. Quality of life was assessed before treatment and at the end of treatment. Quality of life improved for all veterans and the improvement was more significant for those who abstained from alcohol throughout treatment. Severity of psychiatric symptom was associated with worse quality of life. This study demonstrates the importance of addressing social functioning in veterans with dual diagnosis.
精神疾病的诊断对生活质量有负面影响。患有精神疾病的人在身体、心理、认知、社交和职业功能方面存在问题。本研究旨在检查双重诊断退伍军人的生活质量变化。所有退伍军人都参与了一项治疗研究，该研究使用纳曲酮、双硫仑、纳曲酮/双硫仑组合或安慰剂治疗酒精依赖，为期12周。在治疗前和治疗结束时评估生活质量。所有退伍军人的生活质量都有所改善，对于在整个治疗过程中戒酒的人来说，改善更为显著。精神症状的严重程度与较差的生活质量相关。本研究证明了在双重诊断退伍军人中解决社交功能问题的重要性。
