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[下肢急性缺血与硬膜外布比卡因长期治疗]

[Acute ischemia of lower limb and long-term treatment with epidural bupivacaine].

作者信息

Miralles F S, Robles E, Carpintero F, Robles A, Alonso B, López F

机构信息

Unidad de Dolor, Servicio de Anestesiología, Hospital Virgen de la Arrixaca, Murcia.

出版信息

Rev Esp Anestesiol Reanim. 1990 May-Jun;37(3):160-3.

PMID:2389077
Abstract

We report the treatment of an ischemic lower limb (arterial obstruction shown by angiography at popliteal level, proximal to common tibioperoneal artery) with 0.125% and 0.20% epidural bupivacaine, which was continuously administered by pump during 30 days. Simultaneously, 8 mg morphine chloride was administered every 24 hours by epidural route, anticoagulation with heparin was started, and transcutaneous electrical stimulation was used. The favorable outcome, with sufficient peripheral revascularization, permitted to preserve the limb. During therapy no sign of cardiac toxicity attributable to bupivacaine was detected.

摘要

我们报告了对一例缺血性下肢(血管造影显示腘动脉水平、胫腓总动脉近端存在动脉阻塞)患者使用0.125%和0.20%的硬膜外布比卡因进行治疗的情况,通过泵持续给药30天。同时,每24小时经硬膜外途径给予8毫克吗啡氯盐,开始使用肝素进行抗凝,并采用经皮电刺激。最终获得了良好的结果,外周血管充分再通,得以保住肢体。治疗期间未检测到布比卡因所致的心脏毒性迹象。

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