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甲状腺切除术:一种新型的经内镜口腔前庭入路。

Thyroidectomy: a novel endoscopic oral vestibular approach.

机构信息

Department of General Surgery, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, P.R. China.

Department of General Surgery, the First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, P.R. China.

出版信息

Surgery. 2014 Jan;155(1):33-8. doi: 10.1016/j.surg.2013.06.010. Epub 2013 Jul 24.

Abstract

BACKGROUND

To date, no report has discussed endoscopic thyroidectomy using the oral vestibular approach (ETOVA). The objective of this study was to evaluate the feasibility, safety, efficacy, and cosmetic results of endoscopic thyroidectomy involving this surgical approach.

METHODS

Twenty-four patients with benign thyroid nodules were randomized into the ETOVA (n = 12) and the endoscopic thyroidectomy by areola approach (ETAA) groups (n = 12). Therapeutic effects were assessed at follow-up by physical examination. All patients were followed to evaluate thyroid function and scar formation from endoscopic treatment.

RESULTS

Complete resection of all the lesions was performed endoscopically, and no conversion to open surgery was needed. There was no difference between the 2 groups with respect to surgical time (60.4 vs 59.6 min), blood loss (10.8 vs 13.8 mL), postoperative hospital stay (4.9 vs 4.6 d), or cost of surgery (17.6 vs 17.4 thousand yuan). Patients who underwent the areola approach had 3 scars, 10 × 2 mm, 5 × 1 mm, and 5 × 1 mm in size, all of which were visible at the 6-month follow-up. Patients in the ETOVA group did not have any scars. Follow-up showed a significant difference (P = .019) in the satisfaction score between the ETOVA (2.33 ± 0.65) and the ETAA group (1.58 ± 0.79). Imaging showed that all patients had complete resection and no residual disease. Severe complications such as subcutaneous accumulation of blood and fluid, superior or recurrent laryngeal nerve injury, and parathyroid dysfunction were not observed.

CONCLUSION

ETOVA was found to be safe and feasible and did not leave any scars; however, large-scale, randomized clinical trials are necessary for confirmation.

摘要

背景

迄今为止,尚无文献报道经口前庭入路内镜甲状腺切除术(ETOVA)。本研究旨在评估该手术入路内镜甲状腺切除术的可行性、安全性、疗效和美容效果。

方法

将 24 例良性甲状腺结节患者随机分为 ETOVA 组(n=12)和乳晕入路内镜甲状腺切除术(ETAA)组(n=12)。通过体格检查在随访时评估治疗效果。所有患者均接受内镜治疗后的甲状腺功能和疤痕形成随访。

结果

所有病变均经内镜完全切除,无需转为开放性手术。两组的手术时间(60.4 分钟比 59.6 分钟)、出血量(10.8 毫升比 13.8 毫升)、术后住院时间(4.9 天比 4.6 天)和手术费用(17.6 千元比 17.4 千元)无差异。乳晕入路组患者有 3 处疤痕,大小分别为 10×2 毫米、5×1 毫米和 5×1 毫米,均在 6 个月随访时可见。ETOVA 组患者无任何疤痕。随访时 ETOVA 组(2.33±0.65)和 ETAA 组(1.58±0.79)的满意度评分差异有统计学意义(P=0.019)。影像学检查显示所有患者均完全切除,无残留疾病。未观察到皮下积血积液、喉上或喉返神经损伤和甲状旁腺功能减退等严重并发症。

结论

ETOVA 安全可行,且不留疤痕;但仍需要大规模、随机临床试验加以证实。

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