Department of Chemistry, Imperial College London, London, UK.
Chirality. 2013 Nov;25(11):692-700. doi: 10.1002/chir.22194. Epub 2013 Jul 26.
Dimethylaluminum triflate-mediated activation of tetrafluorobenzoates of enantiomerically pure bromohydrins results in enantiospecific polyene cyclizations. The initiation of cyclization by enantiomerically pure bromonium ions and subsequent propagation is not subject to catastrophic erosion of enantiomeric purity by any intramolecular or intermolecular bromonium ion-to-alkene transfer.
三氟甲磺酸二甲铝介导的对映纯溴代醇的四氟苯甲酸酯的活化导致对映选择性聚烯环化。通过对映纯溴翁离子引发环化，随后进行链增长，不会发生任何分子内或分子间溴翁离子到烯烃转移对内消旋纯度的灾难性侵蚀。
