Department of Physics and Biophysics, Institute of Biosciences, UNESP Univ Estadual Paulista, Botucatu, São Paulo, Brazil and Institute of Basic Science and Health, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Bioinformatics. 2013 Oct 1;29(19):2505-6. doi: 10.1093/bioinformatics/btt377. Epub 2013 Jul 26.
Network-level visualization of functional data is a key aspect of both analysis and understanding of biological systems. In a continuing effort to create clear and integrated visualizations that facilitate the gathering of novel biological insights despite the overwhelming complexity of data, we present here the GrAph LANdscape VisualizaTion (GALANT), a Cytoscape plugin that builds functional landscapes onto biological networks. By using GALANT, it is possible to project any type of numerical data onto a network to create a smoothed data map resembling the network layout. As a Cytoscape plugin, GALANT is further improved by the functionalities of Cytoscape, the popular bioinformatics package for biological network visualization and data integration.
功能数据的网络级可视化是分析和理解生物系统的关键方面。为了创建清晰、集成的可视化效果，以便即使面对数据的压倒性复杂性，也能收集新的生物学见解，我们在这里提出了 GrAph LANdscape VisualizaTion（GALANT），这是一个 Cytoscape 插件，可将功能景观构建到生物网络上。通过使用 GALANT，可以将任何类型的数值数据投影到网络上，以创建类似于网络布局的平滑数据图。作为 Cytoscape 的一个插件，GALANT 进一步通过 Cytoscape 的功能得到了增强，Cytoscape 是用于生物网络可视化和数据集成的流行生物信息学软件包。
