Vieira Mário, Rocha E Silva A, Silva Emílio, Sampaio Sérgio, Dias Pedro Paz, Teixeira José Fernando
Serviço de Angiologia e Cirurgia Vascular do Centro Hospital de São João, Porto, Portugal.
Rev Port Cir Cardiotorac Vasc. 2012 Jul-Sep;19(3):163-6.
Presentation of 3 consecutive cases of coronary-subclavian steal syndrome, with special attention to clinical evolution, diagnosis, treatment strategies and outcomes.
We present three consecutive cases of male patients, aged 60 to 69 years (average: 63 years) with hypertension, dyslipidemia, and smoking as the most prevalent cardiovascular risk factors. The 3 cases had a history of previous coronary revascularization using the left internal mammary artery to the anterior descending coronary, with an interval of 4 months to 4 years before the onset of symptoms, 2 of the cases with stable angina, 1 with V4 to V6 ST segment depression in the exercise test and 1 with myocardial infarction with no ST segment elevation. None of the patients had left upper limb claudication. In 2 patients, no left radio-cubital pulse was detected at rest being weak in the third. All patients had atherosclerotic obliteration of the left subclavian artery, 2 with occlusion and 1 with stenosis >90%. Cardiac catheterization was the diagnostic exame in all cases. The interval between diagnosis and intervention was 6 to 13 weeks (median of 9 weeks). We chose the endovascular treatment with balloon expandable stent. The preferred access route was the left humeral artery in 2 cases and the femoral artery in the third.
In all patients the revascularization was achieved, without residual stenosis. Angiography after revascularization, disclosed antegrade flow in all patients through the left internal mammary artery. Recovery of the symmetry of pulses was noticed in all the patients, no signs or symptoms of myocardial ischemia were presented in two of them, with nonspecific pre-cordial symptoms remained in the third, after effort. All patients were discharged with dual antiplatelet therapy for a period not less than 3 months.
The coronary-subclavian steal syndrome is a rare cause of myocardial ischemia after coronary revascularization (0.1% to 6%), as a result of proximal arterial occlusive disease, with subsequent hemodynamic, being atherosclerosis the main etiology. Although the surgical route has been the treatment of choice in the past, endovascular revascularization emerged nowadays as the first-line treatment, with recent studies demonstrating high patency at the 2nd and 5th year after angioplasty (100% and 85% to 95%) and low morbidity and mortality. Further doubts arise about the role of double antiplatelet therapy, having been chosen, in this series, treatment of at least 3 months.
介绍3例连续性冠状动脉-锁骨下动脉盗血综合征病例,特别关注其临床进展、诊断、治疗策略及结果。
我们呈现3例连续性男性患者,年龄在60至69岁之间(平均63岁),高血压、血脂异常和吸烟是最常见的心血管危险因素。这3例患者既往均有使用左乳内动脉至冠状动脉前降支进行冠状动脉血运重建的病史,症状出现前的间隔时间为4个月至4年,其中2例有稳定型心绞痛,1例运动试验时V4至V6导联ST段压低,1例为非ST段抬高型心肌梗死。所有患者均无左上肢间歇性跛行。2例患者静息时未触及左桡动脉搏动,第3例较弱。所有患者均存在左锁骨下动脉粥样硬化闭塞,2例为闭塞,1例为狭窄>90%。所有病例均通过心脏导管检查进行诊断。诊断与干预之间的间隔时间为6至13周(中位数为9周)。我们选择使用球囊扩张支架进行血管内治疗。2例患者首选的入路途径为左肱动脉,第3例为股动脉。
所有患者均实现了血运重建,无残余狭窄。血运重建后的血管造影显示,所有患者左乳内动脉均有顺行血流。所有患者均注意到脉搏对称性恢复,其中2例无心肌缺血的体征或症状,第3例在运动后仍有非特异性心前区症状。所有患者出院时均接受不少于3个月的双联抗血小板治疗。
冠状动脉-锁骨下动脉盗血综合征是冠状动脉血运重建后心肌缺血的罕见原因(0.1%至6%)
,是近端动脉闭塞性疾病导致血流动力学改变的结果,动脉粥样硬化是主要病因。尽管过去手术途径一直是首选治疗方法,但如今血管内血运重建已成为一线治疗方法,最近的研究表明血管成形术后第2年和第5年的通畅率较高(分别为100%和85%至95%),且发病率和死亡率较低。关于双联抗血小板治疗的作用也存在更多疑问,在本系列研究中,选择了至少3个月的治疗。