Department of Immunobiology, 1501 N. Campbell Ave, PO Box 245221, Rm. 6122 AHSC, University of Arizona, Tucson, AZ 85724, USA.
Curr Stem Cell Res Ther. 2013 Sep;8(5):394-9. doi: 10.2174/1574888x11308050006.
Umbilical cord tissue (CT) can provide a virtually unlimited source of multipotent mesenchymal stem cells (MSC) that can potentially be used in a variety of regenerative medicine and tissue engineering applications. Cord tissue segments can be frozen and preserved in liquid nitrogen dewars for prolonged periods of time, having been frozen in time at the peak of biological activity. CT stem cells are capable of giving rise to various mesenchymal and non-mesenchymal cell lineages including bone, cartilage, fat and neurons. Thus, CT stem cells are candidates to develop stem cell-based therapies for a wide variety of diseases including cardiovascular, ophthalmic, orthopedic and neurological applications. CT is currently being used in several regenerative medicine clinical studies, examples of which include treatment of graftversus- host disease and non-healing bone fractures. CT represents an additional source of stem cells that have both immediate and future applications for the individual donor.
脐带组织 (CT) 可以提供几乎无限量的多能间充质干细胞 (MSC)，这些干细胞可能用于各种再生医学和组织工程应用。脐带组织段可以在液氮杜瓦瓶中冷冻保存很长时间，在生物活性的高峰期被及时冷冻。CT 干细胞能够产生各种间充质和非间充质细胞谱系，包括骨、软骨、脂肪和神经元。因此，CT 干细胞是开发基于干细胞的治疗方法的候选者，用于治疗多种疾病，包括心血管、眼科、骨科和神经系统疾病。CT 目前正在用于几项再生医学临床研究中，例如治疗移植物抗宿主病和骨不愈合。CT 是干细胞的另一种来源，它为个体供体提供了即时和未来的应用。
