AuxoCell Laboratories, Inc., 245 First Street, Cambridge, MA 02142, USA.
Placenta. 2011 Oct;32 Suppl 4:S311-5. doi: 10.1016/j.placenta.2011.06.010. Epub 2011 Jul 6.
This review focuses on the therapeutic potential of stem cells harvested from the Wharton's Jelly of the human umbilical cord. Recently, investigators have found that a potent stem cell population exists within the Wharton's Jelly. In this review, the authors define a new subset of stem cells, termed perinatal stem cells, and compare them to other sources of stem cells. Furthermore, cryopreservation of Wharton's Jelly stem cells is described for potential use in future cell based therapies and/or regenerative medicine applications. Current evidence of the application of mesenchymal stem cells from various sources in both pre-clinical and clinical trials is reviewed in the context of potential indications of use for Wharton's Jelly derived mesenchymal stem cells.
这篇综述专注于从人脐带华通氏胶中提取的干细胞的治疗潜力。最近，研究人员发现华通氏胶中存在一种强大的干细胞群体。在这篇综述中，作者定义了一种新的干细胞亚群，称为围产干细胞，并将其与其他来源的干细胞进行比较。此外，还描述了华通氏胶干细胞的冷冻保存，以便将来用于基于细胞的治疗和/或再生医学应用。在综述中，根据华通氏胶衍生的间充质干细胞的潜在用途，还回顾了来自不同来源的间充质干细胞在临床前和临床试验中的应用的当前证据。
