Borisenko K K, Shakirov M T, Kubanova A A, Leshchenko G M, Toporovskiĭ L M
Vestn Dermatol Venerol. 1990(4):28-31.
Status of the cell-mediated, humoral immunity, and nonspecific defense factors were examined before and after specific therapy in 40 homosexuals suffering from secondary relapsing and latent early syphilis. The findings evidence that changes in the cell-mediated immunity of homosexual syphilitics essentially differ from those in heterosexuals with syphilis: decreased count of T-helpers and elevated one of T-suppressors evidence impaired ratio of T-lymphocyte subpopulations and immunoregulatory cell imbalance. A significantly increased level of C4 complement component was observed, evidencing a deficiency of the complement system. These data call for the development of a scheme of immunocorrective therapy for homosexuals suffering from syphilis.
对40例患有二期复发性和早期潜伏梅毒的同性恋者在特异性治疗前后的细胞介导免疫、体液免疫及非特异性防御因子状况进行了检查。研究结果表明,同性恋梅毒患者的细胞介导免疫变化与异性恋梅毒患者的变化有本质区别:辅助性T细胞计数减少,抑制性T细胞计数增加,表明T淋巴细胞亚群比例受损及免疫调节细胞失衡。观察到补体C4成分水平显著升高,表明补体系统存在缺陷。这些数据表明需要为患有梅毒的同性恋者制定免疫纠正治疗方案。