Department of Neurosurgery, Chinese People's Liberation Army General Hospital, Chinese People's Liberation Army Postgraduate Medical School, No.28, Fuxing Road, Haidian District, Beijing 100853, China.
J Clin Neurosci. 2013 Dec;20(12):1780-2. doi: 10.1016/j.jocn.2012.11.021. Epub 2013 Jul 26.
The surgical treatment of medication-resistant epilepsy with schizencephaly is difficult. A standardized method of surgical treatment for schizencephalic patients has not yet been established. We present two patients with poorly controlled epilepsy with schizencephaly. The first patient underwent a resection of the right temporal lobe and part of the posterior lip of the schizencephaly, while the other patient underwent a multi-lobe disconnection. Based on the study of these two patients, we conclude that the location of the epileptic zone, reorganization of eloquent areas and anatomical characteristics of the schizencephaly do not allow a universal surgical approach for treating epilepsy with schizencephaly. Every patient has individual characteristics.
药物难治性伴脑裂畸形的癫痫的手术治疗较为困难，目前尚未建立针对脑裂畸形患者的标准化手术治疗方法。我们报告 2 例伴脑裂畸形的癫痫控制不佳的患者，1 例患者行右侧颞叶及部分脑裂后唇切除术，另 1 例患者行多脑叶离断术。基于这 2 例患者的研究，我们得出结论：致痫区的位置、语言区的重组以及脑裂畸形的解剖学特征不允许对伴脑裂畸形的癫痫采用一种通用的手术方法。每位患者均具有个体特征。
