Department of Transfusion Medicine, Aichi Medical University, 1-1, Yazakokarimata, Nagakute, Aichi 480-1195, Japan.
Am J Clin Pathol. 2013 Aug;140(2):219-24. doi: 10.1309/AJCP6SBPOX0UWHEK.
To describe the frequency of adverse reactions (ARs) after transfusion on both per transfused patient and per transfused unit bases.
We performed a retrospective analysis of data available from records of 6 hospitals on the total number of transfusions and documented ARs between January 2008 and December 2009 for RBCs, fresh-frozen plasma (FFP), and platelet concentrates (PCs).
The incidence of ARs to RBCs, FFP, and PCs per transfused unit was 0.6%, 1.3%, and 3.8%, respectively. The incidence of ARs to RBCs, FFP, and PCs per patient was 2.6%, 4.3%, and 13.2%, respectively-almost 3-fold higher. Most RBC-ARs were febrile nonhemolytic transfusion reactions and allergic reactions, whereas most FFP-ARs and PC-ARs were allergic reactions.
The incidence of ARs per transfused patient may reflect better the potential risk of transfusion with blood components, taking into account the characteristics of the transfused patient.
描述以每输注患者和每输注单位为基础的输血后不良反应 (ARs) 的频率。
我们对 6 家医院的记录中 2008 年 1 月至 2009 年 12 月期间的总输血量和记录的 ARs 数据进行了回顾性分析，对象为 RBC、新鲜冷冻血浆 (FFP) 和血小板浓缩物 (PC)。
每输注单位的 RBC、FFP 和 PC 的 AR 发生率分别为 0.6%、1.3%和 3.8%。每输注患者的 RBC、FFP 和 PC 的 AR 发生率分别为 2.6%、4.3%和 13.2%-几乎高 3 倍。大多数 RBC-AR 为发热非溶血性输血反应和过敏反应，而大多数 FFP-AR 和 PC-AR 为过敏反应。
考虑到输注患者的特点，以每输注患者为基础的 AR 发生率可能更好地反映输血相关血液成分的潜在风险。
