针芯活检在恶性淋巴瘤的病理诊断中具有很高的病理医生间可重复性。
Needle-core biopsy in the pathologic diagnosis of malignant lymphoma showing high reproducibility among pathologists.
机构信息
Department of Pathology, Alegent Creighton Health, Omaha, NE, USA.
出版信息
Am J Clin Pathol. 2013 Aug;140(2):238-47. doi: 10.1309/AJCP9ZAGKVJ8PDAX.
OBJECTIVES
To evaluate the role of needle-core biopsy in the pathologic diagnosis of lymphoma.
METHODS
One hundred and five cases with clinical suspicion for lymphoma were studied by 3 hematopathologists mimicking daily diagnostic service. The diagnostic result sheets were analyzed for diagnostic accuracy and reproducibility. The histologic pattern recognition by the 3 hematopathologists was also analyzed.
RESULTS
The overall diagnostic accuracy, based on the consensus diagnosis, was 85% to 87%. High reproducibility of diagnosis in lymphoma was observed among pathologists. The tissue size was associated with the percentage of definitive diagnosis. Histologic patterns were well recognized on core tissues.
CONCLUSIONS
Needle-core biopsy is an effective technique for the diagnosis of lymphoma and should be considered the first-line procedure for cases with suspicion for lymphoma.
目的
评估细针芯活检在淋巴瘤病理诊断中的作用。
方法
3 位血液病理学家模拟日常诊断服务，对 105 例临床疑似淋巴瘤患者进行研究。分析诊断结果表以评估诊断准确性和可重复性。还分析了 3 位血液病理学家对组织学模式的识别。
结果
根据共识诊断，总体诊断准确性为 85%至 87%。病理学家在诊断淋巴瘤方面具有高度的可重复性。组织大小与明确诊断的百分比有关。在芯组织上可以很好地识别组织学模式。
结论
细针芯活检是诊断淋巴瘤的有效技术，应考虑将其作为疑似淋巴瘤病例的一线程序。
Zotero 插件