Department of Cardiac Intensive Care, Great Ormond Street Hospital for Children, London, UK.
J Perinatol. 2013 Aug;33(8):659-60. doi: 10.1038/jp.2012.159.
Refractory pneumothoraces with bronchopleural fistula (BPF) pose a significant challenge in managing critically sick and ventilated neonates. We report a case of the term female neonate being treated with extracorporeal membrane oxygenation (ECMO) support for meconium aspiration and presumed sepsis, with a significant air leak refractory to pleural drainage that was managed using endobronchial application of cyanoacrylate (enbucrilate) glue to seal the leak.
难治性气胸伴支气管胸膜瘘（BPF）对治疗病重和需要通气的新生儿构成重大挑战。我们报告了一例接受体外膜氧合（ECMO）支持治疗胎粪吸入和疑似败血症的足月女性新生儿，存在显著的气胸漏出，经胸腔引流无效，采用支气管内应用氰基丙烯酸酯（粘固剂）胶封闭漏口进行治疗。
