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紧张型精神分裂症:治疗挑战以及电休克治疗可能发挥的新作用?

Catatonic schizophrenia: therapeutic challenges and potentially a new role for electroconvulsive therapy?

作者信息

Philbin Deirdre, Mulryan D, O'Grady M

机构信息

St Brigid's Hospital, Co Galway, Ireland.

出版信息

BMJ Case Rep. 2013 Jul 29;2013:bcr2013009153. doi: 10.1136/bcr-2013-009153.

Abstract

A 36-year-old man with known schizophrenia, presented with increasingly bizarre behaviour. The development of catatonia and subsequent neuroleptic malignant syndrome in itself posed numerous therapeutic challenges. However, following resolution of neuroleptic malignant syndrome, the reintroduction of antipsychotics was not tolerated. This case report proposes a novel use for electroconvulsive therapy as a treatment of mental state, following resolution of neuroleptic malignant syndrome, to facilitate successful reintroduction of antipsychotics.

摘要

一名36岁的已知患有精神分裂症的男子,出现了越来越怪异的行为。紧张症的发展以及随后出现的抗精神病药物恶性综合征本身带来了诸多治疗挑战。然而,在抗精神病药物恶性综合征缓解后,重新使用抗精神病药物却不被耐受。本病例报告提出了电休克治疗的一种新用途,即在抗精神病药物恶性综合征缓解后,作为一种治疗精神状态的方法,以促进成功重新使用抗精神病药物。

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本文引用的文献

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Aripiprazole and neuroleptic malignant syndrome.阿立哌唑与神经阻滞剂恶性综合征
Int Clin Psychopharmacol. 2004 Nov;19(6):351-3. doi: 10.1097/00004850-200411000-00007.
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Neuroleptic malignant syndrome.抗精神病药恶性综合征
Br J Anaesth. 2000 Jul;85(1):129-35. doi: 10.1093/bja/85.1.129.
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Serum iron in catatonia and neuroleptic malignant syndrome.紧张症和抗精神病药恶性综合征中的血清铁
Biol Psychiatry. 1998 Sep 15;44(6):499-507. doi: 10.1016/s0006-3223(98)00109-7.

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