Thomeer Maarten G, Willemssen Francois E, Biermann Katharina K, El Addouli Haroun, de Man Rob A, Ijzermans Jan N, Dwarkasing Roy S
Department of Radiology, Erasmus MC, CA Rotterdam, The Netherlands.
J Magn Reson Imaging. 2014 May;39(5):1259-64. doi: 10.1002/jmri.24281. Epub 2013 Jul 29.
To evaluate the presentation of inflammatory hepatocellular adenomas (HCAs) on hepatocyte phase MRI.
We retrospectively reviewed the MRI features of histologically proven HCAs on hepatocyte phase imaging. Twenty-one lesions (17 with inflammatory subtype) were scanned with gadobenate dimeglumine. Signal intensities of the lesions were assessed in the hepatocyte phase and on the T1-weighted sequences before contrast.
After gadobenate dimeglumine injection, 71% (12/17) of the inflammatory HCAs showed areas of iso- or hyperintensity to the surrounding liver in the hepatocyte phase. In 82% (10/12) of the iso- or hyperintense lesions, this was found over more than 75% of the lesion surface. None of the noninflammatory HCAs showed areas of iso- or hyperintensity to the surrounding liver in the hepatocyte phase. From these 12, 7 were hyperintense on T1-weighting before contrast due to liver steatosis, 2 due to intrinsic hyperintensity (on the in-phase sequence), and 3 were isointense.
In contrast to noninflammatory HCAs, inflammatory HCAs can show areas of iso- to hyperintensity to the surrounding liver in the hepatocyte phase; therefore, other typical imaging features should also be used to distinguish between HCAs and FNHs.
评估炎症性肝细胞腺瘤（HCA）在肝细胞期MRI上的表现。
我们回顾性分析了经组织学证实的HCA在肝细胞期成像的MRI特征。21个病灶（17个为炎症亚型）采用钆贝葡胺进行扫描。在肝细胞期及对比剂注射前的T1加权序列上评估病灶的信号强度。
注射钆贝葡胺后，71%（12/17）的炎症性HCA在肝细胞期显示与周围肝脏等信号或高信号区域。在82%（10/12）的等信号或高信号病灶中，超过75%的病灶表面出现这种情况。非炎症性HCA在肝细胞期均未显示与周围肝脏等信号或高信号区域。在这12个病灶中，7个因肝脏脂肪变性在对比剂注射前T1加权像上呈高信号，2个因固有高信号（同相位序列上），3个呈等信号。
与非炎症性HCA不同，炎症性HCA在肝细胞期可显示与周围肝脏等信号至高信号区域；因此，还应利用其他典型影像学特征来区分HCA与肝局灶性结节性增生（FNH）。
