Yang Fan, Yang Tai-Zhu, Luo Hong, Song Bin
Department of Diagnostic Ultrasound, West China Second Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2013 May;44(3):424-8.
To determine the value of contrast-enhanced ultrasonography (CEUS) in diagnosing ovarian tumors.
Both conventional ultrasonography (CUS) and CEUS were performed in 86 patients with ovarian masses. A total of 106 ovarian masses from those patients were examined for pathological changes. The blood flow and color scores determined by CUS and CEUS and the contrast intensity determined by CEUS were analyzed and compared with the pathological results.
Blood flow was detected in 91 ovarian masses by CUS, with 27 diagnosed as benign and 79 as malignant. Blood flow was detected in 106 ovarian masses by CEUS, with 33 diagnosed as benign and 73 as malignant. CUS had 84.9% diagnostic accuracy, 92.0% sensitivity, 67.7% specificity, 87.3% positive predictive value, and 77.8% negative predictive value. CEUS had 92.5% diagnostic accuracy, 93.3% sensitivity, 90.3% specificity, 95.9% positive predictive value, and 84.8% negatvie predictive value.
CEUS is a better instrument than CUS for diagnosing ovarian tumors through blood flow detection.
确定超声造影（CEUS）在诊断卵巢肿瘤中的价值。
对86例卵巢肿块患者进行常规超声检查（CUS）和CEUS。对这些患者的106个卵巢肿块进行病理检查。分析CUS和CEUS测定的血流和血流分级以及CEUS测定的造影剂强度，并与病理结果进行比较。
CUS检测到91个卵巢肿块有血流信号，其中27个诊断为良性，79个诊断为恶性。CEUS检测到106个卵巢肿块有血流信号，其中33个诊断为良性，73个诊断为恶性。CUS的诊断准确率为84.9%，灵敏度为92.0%，特异度为67.7%，阳性预测值为87.3%，阴性预测值为77.8%。CEUS的诊断准确率为92.5%，灵敏度为93.3%，特异度为90.3%，阳性预测值为95.9%，阴性预测值为84.8%。
通过血流检测，CEUS在诊断卵巢肿瘤方面比CUS更具优势。
