Larralde C, Sotelo J, Montoya R M, Palencia G, Padilla A, Govezensky T, Diaz M L, Sciutto E
Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City.
Arch Pathol Lab Med. 1990 Sep;114(9):926-8.
Tapeworm antigens from Taenia crassiceps performed as well as those antigens from Taenia solium in an enzyme-linked immunosorbent assay for the detection of Cysticercus antibodies in 96 cerebrospinal fluid samples from patients with neurocysticercosis and in 96 CSF samples from patients with other varied neurological ailments. Thus, this manageable murine model of experimental cysticercosis solved the problem of antigen supply for clinical and epidemiological applications, and it provided an immediate means of abundant production of antigens for the wide distribution and standardization of immunodiagnostic tests for cysticercosis.
在一项酶联免疫吸附试验中,来自肥胖带绦虫的绦虫抗原与来自猪带绦虫的抗原表现相当,该试验用于检测96份来自神经囊尾蚴病患者的脑脊液样本以及96份来自患有其他各种神经系统疾病患者的脑脊液样本中的囊尾蚴抗体。因此,这种易于管理的实验性囊尾蚴病小鼠模型解决了临床和流行病学应用中抗原供应的问题,并提供了一种立即大量生产抗原的方法,以便广泛分发并标准化囊尾蚴病免疫诊断试验。