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脑脊液中人类囊尾蚴病的免疫诊断。来自小鼠肥胖带绦虫囊尾蚴的抗原可有效替代来自猪带绦虫的抗原。

Immunodiagnosis of human cysticercosis in cerebrospinal fluid. Antigens from murine Taenia crassiceps cysticerci effectively substitute those from porcine Taenia solium.

作者信息

Larralde C, Sotelo J, Montoya R M, Palencia G, Padilla A, Govezensky T, Diaz M L, Sciutto E

机构信息

Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City.

出版信息

Arch Pathol Lab Med. 1990 Sep;114(9):926-8.

PMID:2390007
Abstract

Tapeworm antigens from Taenia crassiceps performed as well as those antigens from Taenia solium in an enzyme-linked immunosorbent assay for the detection of Cysticercus antibodies in 96 cerebrospinal fluid samples from patients with neurocysticercosis and in 96 CSF samples from patients with other varied neurological ailments. Thus, this manageable murine model of experimental cysticercosis solved the problem of antigen supply for clinical and epidemiological applications, and it provided an immediate means of abundant production of antigens for the wide distribution and standardization of immunodiagnostic tests for cysticercosis.

摘要

在一项酶联免疫吸附试验中,来自肥胖带绦虫的绦虫抗原与来自猪带绦虫的抗原表现相当,该试验用于检测96份来自神经囊尾蚴病患者的脑脊液样本以及96份来自患有其他各种神经系统疾病患者的脑脊液样本中的囊尾蚴抗体。因此,这种易于管理的实验性囊尾蚴病小鼠模型解决了临床和流行病学应用中抗原供应的问题,并提供了一种立即大量生产抗原的方法,以便广泛分发并标准化囊尾蚴病免疫诊断试验。

相似文献

1
Immunodiagnosis of human cysticercosis in cerebrospinal fluid. Antigens from murine Taenia crassiceps cysticerci effectively substitute those from porcine Taenia solium.脑脊液中人类囊尾蚴病的免疫诊断。来自小鼠肥胖带绦虫囊尾蚴的抗原可有效替代来自猪带绦虫的抗原。
Arch Pathol Lab Med. 1990 Sep;114(9):926-8.
2
[Immunodiagnosis of neurocysticercosis: comparative study of antigenic extracts from Cysticercus cellulosae and Taenia crassiceps].[神经囊尾蚴病的免疫诊断:猪囊尾蚴和肥胖带绦虫抗原提取物的比较研究]
Rev Cubana Med Trop. 2000 Sep-Dec;52(3):157-64.
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Cysticercosis immunodiagnosis using 18- and 14-kilodalton proteins from Taenia crassiceps cysticercus antigens obtained by immunoaffinity chromatography.使用通过免疫亲和层析从肥胖带绦虫囊尾蚴抗原中获得的18千道尔顿和14千道尔顿蛋白质进行囊尾蚴病免疫诊断。
J Clin Microbiol. 2005 Jul;43(7):3178-84. doi: 10.1128/JCM.43.7.3178-3184.2005.
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Detection of antigens of larval Taenia solium in the cerebrospinal fluid of patients with the use of HPLC and ELISA.
J Parasitol. 1990 Feb;76(1):69-73.
5
Evaluation of Taenia solium and Taenia crassiceps cysticercal antigens for the serodiagnosis of neurocysticercosis.用于神经囊尾蚴病血清学诊断的猪带绦虫和肥胖带绦虫囊尾蚴抗原评估。
Trop Med Int Health. 2005 Oct;10(10):1005-12. doi: 10.1111/j.1365-3156.2005.01480.x.
6
Detection and characterization of antigens from Taenia solium cysticercus in cerebrospinal fluid.
Acta Leiden. 1989;57(2):101-5.
7
Antigens from Taenia crassiceps cysticerci used in complement fixation, enzyme-linked immunosorbent assay, and western blot (immunoblot) for diagnosis of neurocysticercosis.来自肥胖带绦虫囊尾蚴的抗原用于补体结合试验、酶联免疫吸附测定和免疫印迹法以诊断神经囊尾蚴病。
J Clin Microbiol. 1995 Dec;33(12):3324-5. doi: 10.1128/jcm.33.12.3324-3325.1995.
8
[Evaluation of Cysticercus cellulosae antigens in the immunodiagnosis of human cysticercosis by ELISA].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1988;6(1):32-5.
9
The value of an antigenic fraction of Cysticercus cellulosae in the serodiagnosis of cysticercosis.猪囊尾蚴抗原成分在囊尾蚴病血清诊断中的价值。
Ann Trop Med Parasitol. 1987 Apr;81(2):117-23. doi: 10.1080/00034983.1987.11812103.
10
Improved diagnosis as an aid to better surveillance of Taenia solium cysticercosis, a potential public health threat to Papua New Guinea.改进诊断有助于更好地监测猪带绦虫囊尾蚴病,这对巴布亚新几内亚构成潜在的公共卫生威胁。
P N G Med J. 1995 Dec;38(4):287-94.

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