McKay D, Ell J, Williams R, Taylor F
Department of Ophthalmology, Royal Prince Alfred Hospital, Sydney, Western Australia.
Aust N Z J Ophthalmol. 1990 May;18(2):215-9. doi: 10.1111/j.1442-9071.1990.tb00617.x.
Lymphomatoid granulomatosis is an uncommon clinical problem and even more rarely presents to the ophthalmologist. A case is described in which a 60-year-old Fijian woman presented with sudden, sequential, complete visual loss in association with signs of scleritis. Direct eyewall biopsy and nasal mucosal biopsy confirmed the diagnosis of lymphomatoid granulomatosis. Despite intensive high-dose oral prednisone therapy her vision remained at no light perception and she developed recrudescence of disease necessitating the use of radiotherapy. All systemic investigations failed to show any other organ involvement by the disease process and she remains well. This is the first report of lymphomatoid granulomatosis presenting as sudden blindness.
淋巴瘤样肉芽肿病是一种罕见的临床病症，就诊于眼科医生的情况更为罕见。本文描述了一例病例，一名60岁的斐济女性突然出现连续性完全视力丧失，并伴有巩膜炎体征。直接眼壁活检和鼻黏膜活检确诊为淋巴瘤样肉芽肿病。尽管给予了大剂量口服泼尼松强化治疗，她的视力仍为无光感，且病情复发，需要进行放射治疗。所有全身检查均未发现疾病累及其他器官，她目前情况良好。这是首例以突然失明为表现的淋巴瘤样肉芽肿病报告。
