Zhu Jie, Niu Ai-rong, Zhao Zi-yun
Department of Laboratory Medicine, Qingdao University Medical College, Qingdao, China.
Zhonghua Yi Xue Za Zhi. 2013 Apr 9;93(14):1093-5.
To assess the diagnostic values of urinalysis in urinary tract infections.
A total of 526 urine culture specimens were analyzed by UF-1000i urine analyzers and GEB600 urine chemistry analyzer to determine the sensitivity and specificity of individual and combined analysis of white blood cell, bacteria count and nitrite test in the diagnosis of urinary tract infections. And bacterial culture was used as the gold standard.
The sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate of bacterial count were the highest in individual analysis at 84.3%, 90.5%, 84.3%, 90.5% and 88.2% respectively. The sensitivity, specificity, positive predictive value and accuracy of combined bacterial count and leukocyte was 83.9%, 91.0%, 85.4% and 88.2% respectively while the negative predictive value of white blood cell and nitrite was highest (91.3%). Compared with the combined or single analysis, the combination of three analyses had the highest sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate at 85.4%, 92.6%, 84.7%, 93.0%, 90.3% respectively.
The combined urinalysis may be used as a rapid screening indicator of urinary tract infections.