Mineno Tomoko, Sakai Mai, Ubukata Akira, Nakahara Kazuhide, Yoshimitsu Hitoshi, Kansui Hisao
Laboratory of Medicinal Chemistry, Faculty of Pharmacy, Takasaki University of Health and Welfare, 60 Nakaorui, Takasaki, Gunma 370–0033, Japan.
Chem Pharm Bull (Tokyo). 2013;61(8):870-2. doi: 10.1248/cpb.c13-00072.
An oxidative methyl esterification of aldehydes was effectively achieved. The trivalent indium reagent, indium(III) triflate, was revealed to accelerate the reactions in many cases. Aromatic aldehydes with various substituents were subjected to this method, and each produced the corresponding methyl esters in good to excellent yields within a relatively short reaction time.
醛的氧化甲基酯化反应得以有效实现。三价铟试剂三氟甲磺酸铟在许多情况下被证明能加速反应。带有各种取代基的芳香醛采用此方法，在相对较短的反应时间内，各反应均以良好至优异的产率生成了相应的甲酯。
