因婴儿血管瘤前来就诊的儿童的恶性鉴别诊断。
Malignant differential diagnosis in children referred for infantile hemangioma.
作者信息
Hoornweg Marije J, Theunissen Carla I J M, Hage J Joris, van der Horst Chantal M A M
机构信息
From the *Department of Plastic, Reconstructive and Hand Surgery, Academic Medical Center; and †Department of Plastic and Reconstructive Surgery, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands.
出版信息
Ann Plast Surg. 2015 Jan;74(1):43-6. doi: 10.1097/SAP.0b013e31828bb2d9.
BACKGROUND AND AIM
Early age malignant tumors can mimic benign infantile hemangioma (IH). The purpose of this study was to determine the percentage of patients referred with a diagnosis of IH that were misdiagnosed, including that of those who in fact had malignant lesions and to assess how the misdiagnosis was reached.
METHODS
From April 2003 through December 2009, all records of children, referred with a diagnosis of IH, were studied to determine the definitive diagnosis. Characteristics of the children with malignant diagnoses and of their diagnostic process were retrospectively analyzed.
RESULTS
The referral diagnosis "hemangioma" was recorded in 423 children and confirmed in 89%. Thirty-nine children were rediagnosed with a vascular malformation (7%) or other benign anomalies (2%). The 7 (2%) remaining children were diagnosed with a malignancy.
CONCLUSIONS
In cases where the diagnosis of IH is equivocal, biopsy has to be performed in a specialized center to prevent delay.
背景与目的
早期恶性肿瘤可能会被误诊为婴儿良性血管瘤（IH）。本研究旨在确定被诊断为IH的患者中被误诊的比例，包括那些实际上患有恶性病变的患者，并评估误诊是如何发生的。
方法
从2003年4月至2009年12月，对所有被诊断为IH的儿童记录进行研究以确定最终诊断。对患有恶性疾病的儿童及其诊断过程的特征进行回顾性分析。
结果
423名儿童的转诊诊断为“血管瘤”，其中89%得到确诊。39名儿童被重新诊断为血管畸形（7%）或其他良性异常（2%）。其余7名（2%）儿童被诊断为恶性肿瘤。
结论
在IH诊断不明确的情况下，必须在专业中心进行活检以避免延误。
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