Shu C, Fang K, Luo M, Li Q, Wang Z
Department of Vascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.
Int Angiol. 2013 Oct;32(5):483-91.
The aim of this paper was to analyze the durability and efficacy of emergency thoracic endovascular aortic repair (TEVAR) for acute Stanford type B aortic dissection (TBAD) with malperfusion syndrome.
A retrospective analysis of acute TBAD with spinal cord, kidney, viscera, and extremity malperfusion was performed. Emergency TEVAR to cover primary tear site by stent-graft was strongly suggested to included candidates. Computed tomography (CT) scans and clinical findings were carried out in diagnosis and follow-up.
One hundred twenty-seven TBAD patients (101 men, 46.1±11.4 year, range 3476) who presented with acute end-organ malperfusion, including sudden paraplegia (N.=4), acute renal failure (N.=26), acute viscera ischemia (N.=61) and limb ischemia (N.=36), received aortic stent-grafting 248 hours after onset. Technical success was achieved in all primary TEVAR. The overall endoleak rate was 7.1% (9/127; typeI:3; typeII: 4; typeIV: 2). The 30-day mortality was 0.8% (2/127). 125 patients were followed for 19.1±14.5 (1~86) months, one patient died 50 days post-TEVAR due to myocardial infarction. Four patients required reintervention with additional stent grafts. Follow-up CT angiography showed enlargement of the true lumen and different degrees of thrombosis in the distal false lumen (complete thrombosis in 48, partial thrombosis in 52 and patency in 24).
Emergency TEVAR is an effective method to treat acute TBAD complicated with end-organ malperfusion. Covering of the proximal entry site of TBAD by stent-graft leads to flow increased in the true lumen and thrombosis of the false lumen of varying degree, which may improve end-organ perfusion and restore branch vessels patency.
本文旨在分析急诊胸主动脉腔内修复术(TEVAR)治疗合并灌注不良综合征的急性Stanford B型主动脉夹层(TBAD)的耐久性和疗效。
对合并脊髓、肾脏、内脏及肢体灌注不良的急性TBAD进行回顾性分析。强烈建议将采用覆膜支架覆盖原发破口部位的急诊TEVAR纳入研究对象。在诊断和随访过程中进行计算机断层扫描(CT)及临床检查。
127例TBAD患者(男性101例,年龄46.1±11.4岁,范围3476岁)出现急性终末器官灌注不良,包括突发截瘫(4例)、急性肾衰竭(26例)、急性内脏缺血(61例)及肢体缺血(36例),发病后248小时接受主动脉覆膜支架置入术。所有初次TEVAR均取得技术成功。总体内漏率为7.1%(9/127;I型:3例;II型:4例;IV型:2例)。30天死亡率为0.8%(2/127)。125例患者随访19.1±14.5(1~86)个月,1例患者在TEVAR术后50天因心肌梗死死亡。4例患者需要再次置入覆膜支架进行干预。随访CT血管造影显示真腔扩大,远端假腔出现不同程度血栓形成(完全血栓形成48例,部分血栓形成52例,通畅24例)。
急诊TEVAR是治疗合并终末器官灌注不良的急性TBAD的有效方法。采用覆膜支架覆盖TBAD近端破口部位可使真腔血流增加,假腔不同程度血栓形成,从而改善终末器官灌注,恢复分支血管通畅。