Nocini P F, Procacci P, Albanese M, Trevisiol L, D'agostino A, Girolomoni G, Palma P, Chiarini L, Bertossi D
Department of Surgery, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy.
Department of Clinical Medicine, Section of Dermatology and Venereology, University of Verona, Verona, Italy.
Minerva Stomatol. 2013 Aug;62(8 Suppl 1):79-86. Epub 2013 Aug 1.
Miescher's cheilitis granulomatosa is the monosymptomatic form of Melkersson-Rosenthal Syndrome. Severe macrocheilitis often causes a functional and esthetical impairment of the lip. Conservative treatment represents the first option to face this rare disease. Unfortunately, medical treatment is often ineffective without any significant result as far as swelling and disfigurement are concerned. Reductive cheiloplasty is indicated in all those patients who have failed to respond to medical treatment. Excision of excess tissue may be obtained by means of several surgical techniques. We report a case of a 55-year-old man affected by severe granulomatous cheilitis refractory to any medical treatment and then treated with the use of tongue flap for the reconstruction of the excised lower lip.
米舍尔肉芽肿性唇炎是梅尔克森 - 罗森塔尔综合征的单症状形式。严重的巨唇症常导致唇部功能和美观受损。保守治疗是应对这种罕见疾病的首选方法。不幸的是,就肿胀和毁容而言,药物治疗往往无效,没有任何显著效果。对于所有对药物治疗无反应的患者,均建议进行唇部整形术。可通过多种手术技术切除多余组织。我们报告一例55岁男性患者,患有严重的肉芽肿性唇炎,对任何药物治疗均无效,随后采用舌瓣进行下唇切除后的重建治疗。