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良性疾病切除术后的残胃癌(32例)

[Carcinoma of the gastric stump after resection of benign disease (32 cases)].

作者信息

De Vega D S, García C, Mayoral C, Tamames S

机构信息

Hospital Universitario de San Carlos, III Cátedra de Cirugía, Universidad Complutense de Madrid.

出版信息

Rev Esp Enferm Dig. 1990 May;77(5):327-31.

PMID:2390353
Abstract

Gastric stump carcinomas have a poor prognosis; the etiology, diagnosis and treatment are not well-defined. The authors analyze their experience with 32 patients with carcinoma of the gastric stump after gastric resection for peptic ulcer; the age of the patients was 44-72 years. The period of latency, since the previous resection, was 28 years. At the time of diagnosis, all patients were symptomatic. The radiological study was positive in 69% of cases and endoscopic exploration and biopsy in 100%. 47% of patients could be resected but the surgery was considered radical only in 4. The tumors were always adenocarcinomas; the muscular layer was infiltrated in 86% of cases and to adjacent organs in 52%. 76% of cases presented lymph node metastases and 31% distant metastases. There were 8 postoperative deaths (28%). The five years survival was 4.2%. The poor prognosis of this lesion emphasizes the importance of early diagnosis and treatment as well as that of periodic follow-up of gastrectomized patients older than 50.

摘要

胃残端癌预后较差;其病因、诊断及治疗尚无明确界定。作者分析了32例因消化性溃疡行胃切除术后发生胃残端癌患者的治疗经验;患者年龄为44至72岁。自上次切除术后的潜伏期为28年。确诊时,所有患者均有症状。放射学检查69%的病例呈阳性,内镜检查及活检100%呈阳性。47%的患者可行手术切除,但仅4例手术被视为根治性手术。肿瘤均为腺癌;86%的病例肌层受侵,52%累及邻近器官。76%的病例出现淋巴结转移,31%出现远处转移。术后死亡8例(28%)。五年生存率为4.2%。该病变预后较差,强调了早期诊断和治疗以及对50岁以上胃切除患者进行定期随访的重要性。

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