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预防和治疗孕期骨盆及背部疼痛的干预措施。

Interventions for preventing and treating pelvic and back pain in pregnancy.

作者信息

Pennick Victoria, Liddle Sarah D

机构信息

Cochrane Editorial Unit, The Cochrane Collaboration, 11-13 Cavendish Square, London, UK, W1G 0AN.

出版信息

Cochrane Database Syst Rev. 2013 Aug 1(8):CD001139. doi: 10.1002/14651858.CD001139.pub3.

DOI:10.1002/14651858.CD001139.pub3
PMID:23904227
Abstract

BACKGROUND

More than two-thirds of pregnant women experience low-back pain (LBP) and almost one-fifth experience pelvic pain. Pain increases with advancing pregnancy and interferes with work, daily activities and sleep.

OBJECTIVES

To assess the effects of interventions for preventing and treating pelvic and back pain in pregnancy.

SEARCH METHODS

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (18 July 2012), identified related studies and reviews from the Cochrane Back Review Group search strategy to July 2012, and checked reference lists from identified reviews and studies.

SELECTION CRITERIA

Randomised controlled trials (RCTs) of any treatment to prevent or reduce the incidence or severity of pelvic or back pain in pregnancy.

DATA COLLECTION AND ANALYSIS

Two review authors independently assessed risk of bias and extracted data. Quality of the evidence for outcomes was assessed using the five criteria outlined by the GRADE Working Group.

MAIN RESULTS

We included 26 randomised trials examining 4093 pregnant women in this updated review. Eleven trials examined LBP (N = 1312), four examined pelvic pain (N = 661), and 11 trials examined lumbo-pelvic (LBP and pelvic) pain (N = 2120). Diagnoses ranged from self-reported symptoms to the results of specific tests. All interventions were added to usual prenatal care and unless noted, were compared to usual prenatal care. For LBP, there was low-quality evidence that in general, the addition of exercise significantly reduced pain (standardised mean difference (SMD) -0.80; 95% confidence interval (CI) -1.07 to -0.53; six RCTs, N = 543), and disability (SMD -0.56; 95% CI -0.89 to -0.23; two RCTs, N = 146); and water-based exercise significantly reduced LBP-related sick leave (risk ratio (RR) 0.40; 95% CI 0.17 to 0.92; one RCT, N = 241). Low-quality evidence from single trials suggested no significant difference in pain or function between two types of pelvic support belt, between osteopathic manipulation (OMT) and usual care or sham ultrasound (sham US). Very low-quality evidence suggested that a specially-designed pillow may relieve night pain better than a regular pillow. For pelvic pain, there was moderate-quality evidence that acupuncture significantly reduced evening pain better than exercise; both were better than usual care. Low-quality evidence from single trials suggested that adding a rigid belt to exercise improved average pain but not function; acupuncture was significantly better than sham acupuncture for improving evening pain and function, but not average pain; and evening pain relief was the same following either deep or superficial acupuncture. For lumbo-pelvic pain, there was moderate-quality evidence that an eight- to 20-week exercise program reduced the risk of women reporting lumbo-pelvic pain (RR 0.85; 95% CI 0.73 to 1.00; four RCTs, N = 1344); but a 16- to 20-week training program was no more successful than usual care at preventing pelvic pain (one RCT, N = 257). Low-quality evidence suggested that exercise significantly reduced lumbo-pelvic-related sick leave (RR 0.76; 95% CI 0.62 to 0.94, two RCTs, N = 1062), and improved function. Low-quality evidence from single trials suggested that OMT significantly reduced pain and improved function; either a multi-modal intervention that included manual therapy, exercise and education (MOM) or usual care significantly reduced disability, but only MOM improved pain and physical function; acupuncture improved pain and function more than usual care or physiotherapy; pain and function improved more when acupuncture was started at 26- rather than 20- weeks' gestation; and auricular (ear) acupuncture significantly improved these outcomes more than sham acupuncture.When reported, adverse events were minor and transient.

AUTHORS' CONCLUSIONS: Moderate-quality evidence suggested that acupuncture or exercise, tailored to the stage of pregnancy, significantly reduced evening pelvic pain or lumbo-pelvic pain more than usual care alone, acupuncture was significantly more effective than exercise for reducing evening pelvic pain, and a 16- to 20-week training program was no more successful than usual prenatal care at preventing pelvic or LBP. Low-quality evidence suggested that exercise significantly reduced pain and disability from LBP.There was low-quality evidence from single trials for other outcomes because of high risk of bias and sparse data; clinical heterogeneity precluded pooling. Publication bias and selective reporting cannot be ruled out.Physiotherapy, OMT, acupuncture, a multi-modal intervention, or the addition of a rigid pelvic belt to exercise seemed to relieve pelvic or back pain more than usual care alone. Acupuncture was more effective than physiotherapy at relieving evening lumbo-pelvic pain and disability and improving pain and function when it was started at 26- rather than 20-weeks' gestation, although the effects were small.There was no significant difference in LBP and function for different support belts, exercise, neuro emotional technique or spinal manipulation (SMT), or in evening pelvic pain between deep and superficial acupuncture.Very low-quality evidence suggested a specially-designed pillow may reduce night-time LBP.Further research is very likely to have an important impact on our confidence in the estimates of effect and is likely to change the estimates.  Future research would benefit from the introduction of an agreed classification system that can be used to categorise women according to presenting symptoms.

摘要

背景

超过三分之二的孕妇会经历腰痛(LBP),近五分之一的孕妇会经历骨盆疼痛。疼痛会随着孕期进展而加剧,影响工作、日常活动和睡眠。

目的

评估预防和治疗孕期骨盆及背部疼痛的干预措施的效果。

检索方法

我们检索了Cochrane妊娠与分娩组试验注册库(2012年7月18日),通过Cochrane背部综述组检索策略确定截至2012年7月的相关研究和综述,并查阅了已确定综述和研究的参考文献列表。

选择标准

预防或降低孕期骨盆或背部疼痛发生率或严重程度的任何治疗的随机对照试验(RCT)。

数据收集与分析

两位综述作者独立评估偏倚风险并提取数据。使用GRADE工作组概述的五项标准评估结局证据的质量。

主要结果

在本次更新综述中,我们纳入了26项随机试验,涉及4093名孕妇。11项试验研究腰痛(N = 1312),4项试验研究骨盆疼痛(N = 661),11项试验研究腰骶部(腰痛和骨盆)疼痛(N = 2120)。诊断范围从自我报告的症状到特定检查的结果。所有干预措施均添加到常规产前护理中,除非另有说明,均与常规产前护理进行比较。对于腰痛,低质量证据表明,一般而言,增加运动可显著减轻疼痛(标准化均数差(SMD)-0.80;95%置信区间(CI)-1.07至-0.53;6项RCT,N = 543)和残疾(SMD -0.56;95%CI -0.89至-0.23;2项RCT,N = 146);水上运动可显著减少与腰痛相关的病假(风险比(RR)0.40;95%CI 0.17至0.92;1项RCT,N = 241)。单项试验的低质量证据表明,两种骨盆支撑带之间、整骨手法治疗(OMT)与常规护理或假超声(假US)之间在疼痛或功能方面无显著差异。极低质量证据表明,特制枕头可能比普通枕头更能缓解夜间疼痛。对于骨盆疼痛,中等质量证据表明,针灸比运动能更显著地减轻夜间疼痛;两者均优于常规护理。单项试验的低质量证据表明,在运动中添加刚性腰带可改善平均疼痛,但不能改善功能;针灸在改善夜间疼痛和功能方面显著优于假针灸,但对平均疼痛无显著改善;深部或浅部针灸后夜间疼痛缓解情况相同。对于腰骶部疼痛,中等质量证据表明,为期8至20周的运动计划可降低女性报告腰骶部疼痛的风险(RR 0.85;95%CI 0.73至1.00;4项RCT,N = 1344);但为期16至20周的训练计划在预防骨盆疼痛方面并不比常规护理更成功(1项RCT,N = 257)。低质量证据表明,运动可显著减少与腰骶部相关的病假(RR 0.76;95%CI 0.62至0.94,2项RCT,N = 1062),并改善功能。单项试验的低质量证据表明,OMT可显著减轻疼痛并改善功能;包括手法治疗、运动和教育的多模式干预(MOM)或常规护理均可显著降低残疾,但只有MOM可改善疼痛和身体功能;针灸比常规护理或物理治疗更能改善疼痛和功能;在妊娠26周而非20周开始针灸时,疼痛和功能改善更明显;耳针(耳部)针灸比假针灸更能显著改善这些结局。报告的不良事件轻微且短暂。

作者结论

中等质量证据表明,根据孕期阶段量身定制的针灸或运动比单独的常规护理能更显著地减轻夜间骨盆疼痛或腰骶部疼痛,针灸在减轻夜间骨盆疼痛方面比运动显著更有效,为期16至20周的训练计划在预防骨盆或腰痛方面并不比常规产前护理更成功。低质量证据表明,运动可显著减轻腰痛引起的疼痛和残疾。由于偏倚风险高和数据稀少,单项试验中关于其他结局的证据质量低;临床异质性妨碍了合并分析。不能排除发表偏倚和选择性报告。物理治疗、OMT、针灸、多模式干预或在运动中添加刚性骨盆腰带似乎比单独的常规护理更能缓解骨盆或背部疼痛。针灸在缓解夜间腰骶部疼痛和残疾以及改善疼痛和功能方面比物理治疗更有效,且在妊娠26周而非20周开始针灸时效果更明显,尽管效果较小。不同支撑带、运动、神经情绪技术或脊柱推拿(SMT)在腰痛和功能方面无显著差异,深部和浅部针灸在夜间骨盆疼痛方面也无显著差异。极低质量证据表明,特制枕头可能减轻夜间腰痛。进一步的研究很可能对我们对效应估计的信心产生重要影响,并可能改变估计值。未来的研究将受益于引入一个商定的分类系统,该系统可用于根据呈现的症状对女性进行分类。

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