Abdin Edimansyah, Subramaniam Mythily, Vaingankar Janhavi Ajit, Chong Siow Ann
Corresponding author: Research Division, Institute of Mental Health, Buangkok Green Medical Park, 10 Buangkok View, Singapore 539747.
Alcohol Alcohol. 2014 Jan-Feb;49(1):103-8. doi: 10.1093/alcalc/agt126. Epub 2013 Jul 31.
The aim of the study was to define predictors of transition from alcohol use to disorders, and their remission, among adults residing in Singapore.
The Singapore Mental Health Study was a cross-sectional survey conducted from December 2009 to December 2010. Information on alcohol use, regular use, DSM-IV criteria for abuse and dependence, and remission among 6616 respondents was obtained with the Composite International Diagnostic Interview.
The prevalence of lifetime alcohol use (drinking at least once in the lifetime) and regular use (ever drinking at least 12 drinks in a 12-month period) was 66.6 and 32%, respectively. Of the regular drinkers, 10.1% progressed into alcohol abuse; 6.9% of abusers turned to alcohol dependence and 16.6 and 7.1% of those with history of alcohol abuse and/or dependence subsequently reported remission defined as cessation of alcohol use and the absence of any symptoms for at least 2 years before interview. Transitions to regular use and to dependence were associated with younger age, Indian ethnicity and an early age of onset of drinking, and women had a higher risk than men of transition from abuse to dependence. Remissions were associated with older age, Malay ethnicity and late age of onset.
The rates of alcohol use and transition to disorders were lower than in other developing countries that have been studied. Sociodemographic predictors include younger age of onset of drinking, something that intervention programs and preventive strategies in Singapore should note.
本研究旨在确定新加坡成年人中从饮酒过渡到酒精使用障碍及其缓解的预测因素。
新加坡精神健康研究是一项于2009年12月至2010年12月进行的横断面调查。通过综合国际诊断访谈获取了6616名受访者的饮酒情况、经常饮酒情况、DSM-IV滥用和依赖标准以及缓解情况等信息。
终生饮酒（一生中至少饮酒一次）和经常饮酒（在12个月期间饮酒至少12次）的患病率分别为66.6%和32%。在经常饮酒者中，10.1%发展为酒精滥用；6.9%的滥用者发展为酒精依赖，有酒精滥用和/或依赖史的受访者中，分别有16.6%和7.1%随后报告缓解，缓解定义为在访谈前至少2年停止饮酒且无任何症状。向经常饮酒和依赖的转变与年龄较小、印度族裔以及较早开始饮酒有关，女性从滥用转变为依赖的风险高于男性。缓解与年龄较大、马来族裔以及较晚开始饮酒有关。
饮酒率和向酒精使用障碍的转变率低于其他已研究的发展中国家。社会人口学预测因素包括较早开始饮酒，这是新加坡的干预项目和预防策略应注意的方面。
