Al-Brahim Nabeel, Zaki Ashraf H, El-Merhi Khaled, Ahmad Mahmoud S
Department of Pathology, Farwaniya Hospital, Salmiya, Kuwait 22034.
Ear Nose Throat J. 2013 Jul;92(7):E1-4. doi: 10.1177/014556131309200712.
Kaposi sarcoma is a malignant vascular neoplasm uncommonly seen in immunosuppressed patients. Herein we report an unusual case of tonsillar Kaposi sarcoma in a patient with membranous glomerulonephritis treated with prednisolone and cyclosporine. The patient presented after 10 months of starting the treatment with a tonsillar mass. Histological examination was typical of monomorphic spindle cell proliferation with slit-like vascular channels. The tumor cells expressed CD34, D2-40 and positive nuclear stain for HHV-8. Kaposi sarcoma is associated with immunosuppression and rarely occurs in the tonsil. Clinicians should be aware of this rare presentation of Kaposi sarcoma.
卡波西肉瘤是一种恶性血管肿瘤，在免疫抑制患者中不常见。在此，我们报告一例罕见的扁桃体卡波西肉瘤病例，患者为一名患有膜性肾小球肾炎的患者，正在接受泼尼松龙和环孢素治疗。该患者在开始治疗10个月后出现扁桃体肿物。组织学检查显示为典型的单形性梭形细胞增殖，伴有裂隙样血管腔隙。肿瘤细胞表达CD34、D2-40，并且HHV-8核染色呈阳性。卡波西肉瘤与免疫抑制相关，很少发生于扁桃体。临床医生应了解卡波西肉瘤的这种罕见表现。
