Wen Jian-Guo, Cui Lin-Gang, Li Yi-Dong, Shang Xiao-Ping, Zhu Wen, Zhang Rui-Li, Meng Qing-Jun, Zhang Sheng-Jun
Urodynamic Center and Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Henan Key-disciplines Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
J Huazhong Univ Sci Technolog Med Sci. 2013 Aug;33(4):563-566. doi: 10.1007/s11596-013-1159-y. Epub 2013 Aug 1.
We performed a retrospective, case-control study to evaluate whether the urine flow acceleration (UFA, mL/s(2)) is superior to maximum uroflow (Qmax, mL/s) in diagnosing bladder outlet obstruction (BOO) in patients with benign prostatic hyperplasia (BPH). In this study, a total of 50 men with BPH (age: 58±12.5 years) and 50 controls (age: 59±13.0 years) were included. A pressure-flow study was used to determine the presence of BOO according to the recommendations of Incontinence Control Society (ICS). The results showed that the UFA and Qmax in BPH group were much lower than those in the control group [(2.05±0.85) vs. (4.60±1.25) mL/s(2) and (8.50±1.05) vs. (13.00±3.35) mL/s] (P<0.001). According to the criteria (UFA<2.05 mL/s(2), Qmax<10 mL/s), the sensitivity and specificity of UFA vs. Qmax in diagnosing BOO were 88%, 75% vs. 81%, 63%. UFA vs. Omax, when compared with the results of P-Q chart (the kappa values in corresponding analysis), was 0.55 vs. 0.35. The prostate volume, post void residual and detrusor pressure at Qmax between the two groups were 28.6±9.8 vs. 24.2±7.6 mL, 60.4±1.4 vs. 21.3±2.5 mL and 56.6±8.3 vs. 21.7±6.1 cmH2O, respectively (P<0.05). It was concluded that the UFA is a useful urodynamic parameter, and is superior to Qmax in diagnosing BOO in patients with BPH.
我们进行了一项回顾性病例对照研究，以评估尿流加速（UFA，毫升/秒²）在诊断良性前列腺增生（BPH）患者膀胱出口梗阻（BOO）方面是否优于最大尿流率（Qmax，毫升/秒）。在本研究中，共纳入50例BPH男性患者（年龄：58±12.5岁）和50例对照者（年龄：59±13.0岁）。根据尿失禁控制协会（ICS）的建议，采用压力-流率研究来确定是否存在BOO。结果显示，BPH组的UFA和Qmax远低于对照组[（2.05±0.85）对（4.60±1.25）毫升/秒²以及（8.50±1.05）对（13.00±3.35）毫升/秒]（P<0.001）。根据标准（UFA<2.05毫升/秒²，Qmax<10毫升/秒），UFA与Qmax在诊断BOO时的敏感性和特异性分别为88%、75%对81%、63%。与P-Q图结果（相应分析中的kappa值）相比，UFA与Omax分别为0.55对0.35。两组之间的前列腺体积、排尿后残余尿量和Qmax时的逼尿肌压力分别为28.6±9.8对24.2±7.6毫升、60.4±1.4对21.3±2.5毫升以及56.6±8.3对21.7±6.1厘米水柱（P<0.05）。结论是，UFA是一个有用的尿动力学参数，在诊断BPH患者的BOO方面优于Qmax。
