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男性下尿路症状(LUTS)和良性前列腺增生(BPH)。

Male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH).

机构信息

Department of Urology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, J8 142, Dallas, TX 75390-9110, USA.

出版信息

Med Clin North Am. 2011 Jan;95(1):87-100. doi: 10.1016/j.mcna.2010.08.013.

Abstract

Male lower urinary tract symptoms, benign prostatic hyperplasia, enlargement of the prostate, and bladder outlet obstruction are common among aging men and will increase in socioeconomic and medical importance at a time of increased life expectancy and aging of the baby boomer generation. This article reviews the epidemiology, management, and therapeutic options for these conditions. In patients bothered by moderate to severe symptoms, providers can make educated and differential choices between several classes of drugs, alone or in combination, to treat effectively and improve the symptoms in most men. Despite the efficacy of medical therapy, there will be patients who require referral to a urologist either early, to rule out prostate cancer and other conditions, or later, after initial medical therapy and lifestyle management has failed. Perhaps as many as 30% of patients fail to achieve sufficient symptom improvement with medication, lifestyle adjustment, and fluid management, and may require more invasive or surgical treatment options.

摘要

男性下尿路症状、良性前列腺增生、前列腺增大和膀胱出口梗阻在老年男性中很常见,并且在预期寿命延长和婴儿潮一代老龄化的时代,它们在社会经济和医学方面的重要性将会增加。本文回顾了这些疾病的流行病学、管理和治疗选择。对于有中度至重度症状的患者,医生可以在几类药物之间做出明智和有区别的选择,单独使用或联合使用,以有效地治疗并改善大多数男性的症状。尽管药物治疗有效,但仍有一些患者需要转介给泌尿科医生,要么是早期排除前列腺癌和其他疾病,要么是在初始药物治疗和生活方式管理失败后。多达 30%的患者可能无法通过药物、生活方式调整和液体管理获得足够的症状改善,可能需要更具侵入性或手术治疗选择。

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