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贲门失弛缓症行赫勒肌切开术后的翻修手术:聚焦手术入路的比较分析

Revisional surgery after heller myotomy for treatment of achalasia: a comparative analysis focusing on operative approach.

作者信息

Gouda Biswanath P, Nelson Thomas, Bhoyrul Sunil

机构信息

Department of General Surgery, P.D.Hinduja National Hospital and Medical Research Center, Veer Savarkar Marg, Mahim Mumbai, 400016 India.

出版信息

Indian J Surg. 2012 Aug;74(4):309-13. doi: 10.1007/s12262-011-0402-7. Epub 2012 Jan 21.

Abstract

Surgical myotomy is the gold standard in therapy for achalasia, but treatment failures occur and require revisional surgery. A MEDLINE search of peer-reviewed articles published in English from 1970 to December 2008 was performed using the following terms: esophageal achalasia, Heller myotomy, and revisional surgery. Thirty-three articles satisfied our inclusion criteria. A total of 12,727 patients, with mean age of 43.3 years (males 46% and females 50%), underwent Heller myotomy (open 94.8% and laparoscopic 5.2%). Revisional surgery was performed in 6.19%. Procedures performed included revision of the original myotomy or creation of a new myotomy with or without an antireflux procedure or esophagectomy. Reasons for reoperation were incomplete myotomy (51.8%), onset of reflux (34%), megaesophagus (16.2%), and esophageal carcinoma (3.04%). Systematic review of the literature for revisional surgery following Heller myotomy revealed a 6.19% rate of reoperation with a low mortality rate.

摘要

手术肌切开术是贲门失弛缓症治疗的金标准,但仍会出现治疗失败的情况,需要进行翻修手术。使用以下术语对1970年至2008年12月以英文发表的同行评审文章进行了MEDLINE检索:食管贲门失弛缓症、海勒肌切开术和翻修手术。33篇文章符合我们的纳入标准。共有12727例患者接受了海勒肌切开术,平均年龄43.3岁(男性占46%,女性占50%),其中开放手术占94.8%,腹腔镜手术占5.2%。翻修手术的比例为6.19%。实施的手术包括对原肌切开术进行翻修或进行新的肌切开术,同时可选择或不选择抗反流手术或食管切除术。再次手术的原因包括肌切开不完全(51.8%)、反流发生(34%)、巨食管(16.2%)和食管癌(3.04%)。对海勒肌切开术后翻修手术的文献系统评价显示,再次手术率为6.19%,死亡率较低。

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