Gouda Biswanath P, Nelson Thomas, Bhoyrul Sunil
Department of General Surgery, P.D.Hinduja National Hospital and Medical Research Center, Veer Savarkar Marg, Mahim Mumbai, 400016 India.
Indian J Surg. 2012 Aug;74(4):309-13. doi: 10.1007/s12262-011-0402-7. Epub 2012 Jan 21.
Surgical myotomy is the gold standard in therapy for achalasia, but treatment failures occur and require revisional surgery. A MEDLINE search of peer-reviewed articles published in English from 1970 to December 2008 was performed using the following terms: esophageal achalasia, Heller myotomy, and revisional surgery. Thirty-three articles satisfied our inclusion criteria. A total of 12,727 patients, with mean age of 43.3 years (males 46% and females 50%), underwent Heller myotomy (open 94.8% and laparoscopic 5.2%). Revisional surgery was performed in 6.19%. Procedures performed included revision of the original myotomy or creation of a new myotomy with or without an antireflux procedure or esophagectomy. Reasons for reoperation were incomplete myotomy (51.8%), onset of reflux (34%), megaesophagus (16.2%), and esophageal carcinoma (3.04%). Systematic review of the literature for revisional surgery following Heller myotomy revealed a 6.19% rate of reoperation with a low mortality rate.
手术肌切开术是贲门失弛缓症治疗的金标准,但仍会出现治疗失败的情况,需要进行翻修手术。使用以下术语对1970年至2008年12月以英文发表的同行评审文章进行了MEDLINE检索:食管贲门失弛缓症、海勒肌切开术和翻修手术。33篇文章符合我们的纳入标准。共有12727例患者接受了海勒肌切开术,平均年龄43.3岁(男性占46%,女性占50%),其中开放手术占94.8%,腹腔镜手术占5.2%。翻修手术的比例为6.19%。实施的手术包括对原肌切开术进行翻修或进行新的肌切开术,同时可选择或不选择抗反流手术或食管切除术。再次手术的原因包括肌切开不完全(51.8%)、反流发生(34%)、巨食管(16.2%)和食管癌(3.04%)。对海勒肌切开术后翻修手术的文献系统评价显示,再次手术率为6.19%,死亡率较低。