Geavlete B, Stănescu F, Moldoveanu C, Jecu M, Adou L, Bulai C, Ene C, Geavlete P
Sf. Ioan Clinical Emergency Hospital, Department of Urology, Bucharest, Romania.
J Med Life. 2013 Jun 15;6(2):140-5. Epub 2013 Jun 25.
The standard non-muscle invasive bladder cancer (NMIBC) endoscopic diagnosis suffers from the frequently unsatisfactory white light evaluation accuracy leading to residual lesions being left behind. Monopolar transurethral resection of bladder tumors (TURBT) is marked by a substantial morbidity rate requiring further amelioration.
Small size tumors (under 1 cm) are feasible for "en bloc" resection. Bipolar TURBT was defined as being able to challenge the gold-standard status of monopolar resection due to the reduced complication rates. Plasma-button vaporization was introduced as a promising large bladder tumors' ablation modality. Narrow band imaging (NBI) cystoscopy became an increasingly popular method of enhancing tumor detection.
The "en bloc" resection of small size or thin pedicle tumors provides the conditions for avoiding tumoral tissue scattering. Bipolar resection is characterized by decreased perioperative bleeding risks and faster patient recovery. Plasma-button vaporization gained confirmation as an innovative approach, able to dispose large tumor bulks under complete control while minimizing the associated morbidity. NBI cystoscopy is a useful tool in identifying CIS lesions, small papillary tumors or extended margins of large tumor formations. As a cost-free technique, it may be extensively used both during the NMIBC initial diagnostic as well as during follow-up evaluation protocol.
Having in mind the various modalities of ameliorating the bladder cancer diagnostic and treatment, NMIBC management should be tailored in accordance with the particularities of each case.
标准的非肌层浸润性膀胱癌(NMIBC)内镜诊断常因白光评估准确性欠佳而导致残留病变。经尿道膀胱肿瘤单极电切术(TURBT)的发病率较高,需要进一步改善。
小尺寸肿瘤(直径小于1 cm)可行“整块”切除。双极TURBT因并发症发生率降低而有望挑战单极切除的金标准地位。等离子体按钮汽化术被引入作为一种有前景的大体积膀胱肿瘤消融方式。窄带成像(NBI)膀胱镜检查成为增强肿瘤检测的一种越来越流行的方法。
小尺寸或细蒂肿瘤的“整块”切除为避免肿瘤组织播散提供了条件。双极切除的特点是围手术期出血风险降低,患者恢复更快。等离子体按钮汽化术作为一种创新方法得到认可,能够在完全控制下处理大体积肿瘤,同时将相关发病率降至最低。NBI膀胱镜检查是识别原位癌(CIS)病变、小乳头状肿瘤或大肿瘤形成的扩展边缘的有用工具。作为一种免费技术,它可广泛用于NMIBC的初始诊断以及随访评估方案中。
考虑到改善膀胱癌诊断和治疗的各种方式,NMIBC管理应根据每个病例的特点进行定制。