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细针穿刺细胞学检查在儿童年龄组头颈部病变中的作用。

Role of fine needle aspiration cytology in head and neck lesions of paediatric age group.

作者信息

Mittra Purnima, Bharti Rajni, Pandey Manmohan Krishna

机构信息

Assistant Professor, Department of Pathology, Rohilkhand Medical College and Hospital , Bareilly-243001, U.P., India .

出版信息

J Clin Diagn Res. 2013 Jun;7(6):1055-8. doi: 10.7860/JCDR/2013/5384.3067. Epub 2013 May 15.

Abstract

CONTEXT

Fine Needle Aspiration Cytology [FNAC] of the head and neck region is well accepted as a diagnostic procedure. Various studies in the context of FNAC in the head and neck region are available for the adult population, but only few studies are available for the paediatric age group.

AIMS

To study the role of fine needle aspiration cytology and its utility in paediatric head and neck lesions.

SETTINGS AND DESIGN

This was a hospital based, prospective study.

METHOD AND MATERIALS

Hundred cases of head and neck lesions of the paediatric age group [0-15 years] were studied for cytomorphology through fine needle aspiration cytology and the results were correlated with the histomorphology.

RESULTS

There was a male predominance in the case distribution among both the sexes in children [55%]. The head and neck lesions were most frequent in the age group of 10-15 years, followed by the age group of 5-10 years than the age group of 0-5 years. Lesions in the cervical lymph nodes constituted 81% of the head and neck lesions and 87% of the adequate smears, followed by those in the skin and subcutaneous tissues [3 cases (3.2%)], the thyroid [4 cases (4.3%)] and the salivary gland [1 case (1%)]. 88.17% cases of head and neck lesions in children were diagnosed as benign on their smears and 11.83% cases were diagnosed as malignant, of which 8 cases of malignant lesions were located in the cervical lymph nodes, 1 case was located in the thyroid and 2 cases of malignant lesions were located in the orbits.

CONCLUSIONS

FNAC is an important and a non-invasive, investigational tool in children for identifying and planning the medical management of inflammatory and infectious conditions. It helped us in indicating the diagnosis of the lesions in congenital or aquired malformations, cystic lesions and benign neoplastic lesions, in which surgical management were needed and we got confirmations on histological examinations. For the malignant lesions, FNAC was a more important investigation tool than an accurate investigation tool, which suggested about the lesions and guided us to do more advanced specific investigations for obtaining the diagnosis.

摘要

背景

头颈部细针穿刺抽吸细胞学检查(FNAC)作为一种诊断方法已被广泛接受。在头颈部FNAC方面,针对成年人群已有各种研究,但针对儿童年龄组的研究较少。

目的

研究细针穿刺抽吸细胞学检查在儿童头颈部病变中的作用及其实用性。

研究地点和设计

这是一项基于医院的前瞻性研究。

方法和材料

通过细针穿刺抽吸细胞学检查对100例儿童年龄组(0 - 15岁)的头颈部病变进行细胞形态学研究,并将结果与组织形态学进行对比。

结果

儿童病例分布中男性占主导(55%)。头颈部病变在10 - 15岁年龄组最为常见,其次是5 - 10岁年龄组,0 - 5岁年龄组相对较少。颈部淋巴结病变占头颈部病变的81%,在足够涂片病例中占87%,其次是皮肤和皮下组织病变[3例(3.2%)]、甲状腺病变[4例(4.3%)]和唾液腺病变[1例(1%)]。儿童头颈部病变涂片诊断为良性的占88.17%,诊断为恶性的占11.83%,其中8例恶性病变位于颈部淋巴结,1例位于甲状腺,2例恶性病变位于眼眶。

结论

FNAC是儿童识别和规划炎症及感染性疾病医疗管理的重要且非侵入性的检查工具。它有助于我们对先天性或后天性畸形、囊性病变和良性肿瘤性病变进行诊断,这些病变需要手术治疗,且我们通过组织学检查得到了证实。对于恶性病变,FNAC是一个比准确诊断工具更重要的检查工具,它提示了病变情况,并指导我们进行更高级的特异性检查以获得诊断。

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本文引用的文献

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Management of common head and neck masses.常见头颈部肿块的管理
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Fine needle aspiration biopsy of pediatric head and neck masses.小儿头颈部肿块的细针穿刺活检
Int J Pediatr Otorhinolaryngol. 2001 Aug 20;60(2):135-40. doi: 10.1016/s0165-5876(01)00522-5.
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Fine-needle aspiration of head and neck masses in children.
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