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A PATHOLOGICAL STUDY OF BENIGN AND MALIGNANT TUMOURS OF SALIVARY GLANDS.涎腺良恶性肿瘤的病理学研究
Med J Armed Forces India. 2000 Oct;56(4):282-286. doi: 10.1016/S0377-1237(17)30208-3. Epub 2017 Jun 12.
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FNAC of salivary gland lesions with histopathological correlation.唾液腺病变的细针穿刺抽吸活检及其组织病理学相关性
Indian J Otolaryngol Head Neck Surg. 2006 Jul;58(3):246-8. doi: 10.1007/BF03050831.
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Salivary gland tumours.
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细针穿刺细胞学检查:唾液腺病变诊断中的可靠工具。

Fine-Needle Aspiration Cytology: A Reliable Tool in the Diagnosis of Salivary Gland Lesions.

作者信息

Kumar Rakesh, Mandal Manit M, Panchal Ajay J, Kapadia Parth B

机构信息

Department of Otorhinolaryngology (ENT), SMIMER, Surat, Gujarat India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5511-5514. doi: 10.1007/s12070-021-02845-w. Epub 2021 Aug 28.

DOI:10.1007/s12070-021-02845-w
PMID:36742936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9895335/
Abstract

Salivary gland lesions comprise for about 2-6.5% of all head and neck neoplasms in adults. They are accessible for FNAC (Fine Needle Aspiration Cytology). The risk of fistula formation and/or tumour implantation are low compared to surgical biopsy. FNAC can also provide a distinction between asalivary and non-salivary lesion, benign and malignant lesions. 67 patients were studied prospectively over 5 years. FNAC was performed pre-operatively and histopathological examination post-operatively in patients who underwent surgery and were willing to participate in the study. 59.7% of the lesions were non-neoplastic and 58.2% were neoplastic (37.3% benign and 20.8% malignant). Pleomorphic adenoma was the most common benign neoplasm while mucoepidermoidand adenoid cystic carcinoma both were the most frequent malignant lesion. Among the non-neoplastic lesions, the most number of cases were of chronic sialadentis. In our study, FNAC has a sensitivity of 94.54% specificity of 80.95% for neoplastic lesions. It was seen that FNAC was a useful diagnostic tool in the evaluation of salivary gland lesions because of its simplicity, excellent patient compliance and rapid diagnosis. This cost effective tool is invaluable in planning the surgical management of the patient.

摘要

唾液腺病变约占成人头颈部肿瘤的2 - 6.5%。它们适合进行细针穿刺抽吸细胞学检查(FNAC)。与手术活检相比,形成瘘管和/或肿瘤种植的风险较低。FNAC还可以区分唾液腺病变和非唾液腺病变、良性病变和恶性病变。对67例患者进行了为期5年的前瞻性研究。对接受手术且愿意参与研究的患者,术前进行FNAC检查,术后进行组织病理学检查。59.7%的病变为非肿瘤性,58.2%为肿瘤性(37.3%为良性,20.8%为恶性)。多形性腺瘤是最常见的良性肿瘤,而黏液表皮样癌和腺样囊性癌均为最常见的恶性病变。在非肿瘤性病变中,慢性涎腺炎病例最多。在我们的研究中,FNAC对肿瘤性病变的敏感性为94.54%,特异性为80.95%。可以看出,FNAC因其操作简单、患者依从性好和诊断迅速,是评估唾液腺病变的一种有用的诊断工具。这种具有成本效益的工具在规划患者的手术治疗中具有重要价值。