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自发性胆管穿孔:儿童中一种罕见但重要的病症。

Spontaneous Biliary Perforations: An Uncommon yet Important Entity in Children.

作者信息

Goel Prabudh, Jain Vishesh, Manchanda Vivek, Sengar Mamta, Gupta Chhabi Ranu, Mohta Anup

机构信息

Assistant Professor, Department of Pediatric Surgery, King George's Medical University , Lucknow, UP, India .

出版信息

J Clin Diagn Res. 2013 Jun;7(6):1201-6. doi: 10.7860/JCDR/2013/5429.3076. Epub 2013 Jun 1.

Abstract

Spontaneous or idiopathic biliary perforations are an infrequently encountered but an important cause of surgical jaundice in paediatric patients and one of the most common causes of surgical jaundice in infancy. A pre-operative diagnosis with a clinical history and physical findings may not be possible in most of the cases. The exact cause of the perforation remains unclear and the diagnosis is made at the time of laparotomy for an acute abdomen. An early, efficient and an effective surgical management is associated with a good prognosis; however, a delay in the correct diagnosis or an inappropriate management may result in bacterial contamination of the biliary ascites, with an unfavourable outcome. The relative rarity of this condition is reflected by the very few case reports, limited case studies and scarcity of published literature.

摘要

自发性或特发性胆穿孔虽不常见,但却是小儿外科黄疸的重要病因,也是婴儿期外科黄疸最常见的病因之一。多数情况下,仅依据临床病史和体格检查结果可能无法进行术前诊断。穿孔的确切原因尚不清楚,通常在因急腹症行剖腹探查时才能确诊。早期、高效且有效的手术治疗预后良好;然而,诊断延误或处理不当可能导致胆汁性腹水发生细菌污染,从而产生不良后果。这种疾病相对罕见,仅有极少的病例报告、有限的病例研究,公开文献也很匮乏,这一点也有所体现。

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本文引用的文献

1
Spontaneous common bile duct perforation presenting as acute abdomen.表现为急腹症的自发性胆总管穿孔
Indian J Surg. 2010 Oct;72(5):407-8. doi: 10.1007/s12262-010-0113-5. Epub 2010 Nov 18.
3
Management of biliary perforation in children.儿童胆穿孔的管理
Afr J Paediatr Surg. 2010 Sep-Dec;7(3):147-50. doi: 10.4103/0189-6725.70413.
7
Clinicopathological analysis of idiopathic perforation of the gallbladder.胆囊特发性穿孔的临床病理分析
Surg Today. 2007;37(8):633-7. doi: 10.1007/s00595-006-3476-2. Epub 2007 Jul 26.
8
Spontaneous perforation of the biliary tract and portal vein thrombosis in infancy.
Pediatr Surg Int. 2008 Mar;24(3):357-9. doi: 10.1007/s00383-007-1954-2. Epub 2007 Jul 17.
9
Bile duct perforation in children: is it truly spontaneous?
Ann Acad Med Singap. 2006 Dec;35(12):905-8.

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